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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urmj</journal-id><journal-title-group><journal-title xml:lang="ru">Уральский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Ural Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-4389</issn><publisher><publisher-name>Ural State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52420/2071-5943-2023-22-1-23-31</article-id><article-id custom-type="elpub" pub-id-type="custom">urmj-1188</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные статьи | Original articles</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original articles</subject></subj-group></article-categories><title-group><article-title>Сравнительный анализ уровня боли, дооперационной тревоги, депрессии и лабораторных показателей при операциях на матке</article-title><trans-title-group xml:lang="en"><trans-title>Comparative analysis of pain levels, preoperative anxiety, depression and laboratory parameters during uterine surgery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>М. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>M. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Максим Олегович Попов </p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Maksim O. Popov </p><p>Ekaterinburg</p></bio><email xlink:type="simple">doctorjosef@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давыдова</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Davidova</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Надежда Степановна Давыдова – доктор медицинских наук, профессор </p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Nadezhda S. Davidova – Doctor of Science (Medicine), Professor </p><p>Ekaterinburg</p></bio><email xlink:type="simple">davidovaeka@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Собетова</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobetova</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галина Вячеславовна Собетова – кандидат медицинских наук, доцент</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Galina V. Sobetova – Ph.D. in medicine, Associate Professor </p><p>Ekaterinburg</p></bio><email xlink:type="simple">sobetova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бердникова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Berdnikova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Альбертовна Бердникова – кандидат медицинских наук </p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Anna A. Berdnikova – Ph.D. in medicine </p><p>Ekaterinburg</p></bio><email xlink:type="simple">anna.berdnikova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воронова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Voronova</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Людмила Николаевна Воронова </p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Ljudmila N. Voronova </p><p>Ekaterinburg</p></bio><email xlink:type="simple">lyuda.voronova.60@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центральная городская клиническая больница № 1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central City Clinical Hospital №1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Уральский государственный медицинский университет;&#13;
Центральная городская клиническая больница № 1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural State Medical University;&#13;
Central City Clinical Hospital №1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2023</year></pub-date><volume>22</volume><issue>1</issue><fpage>23</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Попов М.О., Давыдова Н.С., Собетова Г.В., Бердникова А.А., Воронова Л.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Попов М.О., Давыдова Н.С., Собетова Г.В., Бердникова А.А., Воронова Л.Н.</copyright-holder><copyright-holder xml:lang="en">Popov M.O., Davidova N.S., Sobetova G.V., Berdnikova A.A., Voronova L.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.umjusmu.ru/jour/article/view/1188">https://www.umjusmu.ru/jour/article/view/1188</self-uri><abstract><p>Введение. Исследования показывают низкую эффективность послеоперационного обезболивания у пациенток гинекологического профиля. Психогенный компонент имеет немаловажное значение в формировании послеоперационного болевого синдрома. Цель исследования – установить факторы, влияющие на развитие неконтролируемого болевого синдрома у пациенток, перенесших операции на матке. Материалы и методы. Обследовано 30 пациенток, подвергшихся плановому оперативному лечению в объеме гистерэктомии, консервативной миомэктомии лапароскопическим, лапаротомным доступом или в сочетании с пластической операцией на промежности. Пациентки исследуемых подгрупп не отличались по возрасту, ИМТ, соматическому статусу. Послеоперационное обезболивание проводили эпидуральной аналгезией 0,2 % раствором ропивакаина. Изучали показатели дооперационной тревоги и депрессии (по шкале HADS), динамику показателей уровня С-реактивного белка, глюкозы, лактата, кислотно-основного состояния, гемостаза, а также уровня боли исходно и в послеоперационом периоде, скорость послеоперационного восстановления пациенток, удовлетворенность обезболиванием. Результаты. Наибольшее число достоверных различий в подгруппах было получено при делении по уровню дооперационной тревоги. Пациентки с повышенным уровнем дооперационной тревожности были менее активны в послеоперационном периоде, имели в три раза более высокий уровень С-реактивного белка в день выписки. У пациенток с депрессией уровень глюкозы был достоверно выше по сравнению с подгруппой без признаков дооперационной депрессии на третьи послеоперационные сутки, а уровень С-реактивного белка – на вторые сутки. Данные регрессионного анализа показывают взаимосвязь уровня дооперационной тревоги и неконтролируемой боли в послеоперационном периоде у пациенток гинекологического профиля. Обсуждение. Динамика лабораторных показателей свидетельствует в пользу адекватной анестезиологической и противоболевой защиты в исследуемой группе. Используемый нами протокол противоболевой защиты при проведении оперативного вмешательства на матке позволяет уменьшить уровень послеоперационной боли и увеличить удовлетворенность пациенток обезболиванием. Влияние уровня тревоги и депрессии на выраженность болевого синдрома и течение послеоперационного периода обуславливают необходимость применения шкалы HADS в предоперационном периоде. Пациенткам с симптомами клинически выраженной дооперационной тревоги следует назначать консультацию психотерапевта и анксилолитические препараты на этапе дооперационного обследования. Заключение. Уровень догоспитальной тревоги является значимым фактором, влияющим на развитие неконтролируемого болевого синдрома. Шкала HADS позволяет определить группу «повышенного риска» по развитию неконтролируемой боли в послеоперационном периоде у пациенток, ожидающих операцию на матке, и является скрининговым тестом.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. Studies show a low efficiency of postoperative pain relief, especially in gynecological patients. The psychogenic component is of no small importance in the formation of postoperative pain syndrome. Purpose of the study was to determine the factors influencing the development of uncontrolled pain syndrome in patients who underwent uterine surgery. Materials and methods. We examined 30 patients who underwent elective surgery for hysterectomy, conservative myomectomy by laparoscopic or laparotomy access or in combination with perineal plastic surgery. Patients of the study subgroups did not differ in age, BMI, and somatic status. Epidural analgesia with 0.2 % ropivacaine solution was performed. We studied preoperative anxiety and depression scores (HADS scale), the dynamics of C-reactive protein level, glucose, lactate, acid-base status, hemostasis, and pain level initially and in the postoperative period, postoperative recovery rate of the patients and satisfaction with anesthesia. Results. The greatest number of reliable differences in the subgroups was obtained when dividing by the level of preoperative anxiety. Patients with an elevated level of preoperative anxiety were less active in the postoperative period and had three times higher levels of C-reactive protein on the day of discharge. Patients with depression had significantly higher glucose levels compared to the subgroup without signs of preoperative depression on the third postoperative day, and C-reactive protein levels on the second day. The data of regression analysis show the relationship between the level of preoperative anxiety and uncontrolled pain in the postoperative period in gynecological patients. Discussion. The dynamics of the laboratory indices testify in favor of adequate anesthesia and pain control in the study group. The protocol of pain control during uterine surgery that we use allows us to reduce the level of postoperative pain to acceptable values and increase patients' satisfaction with the recommended analgesia. The impact of anxiety and depression on the severity of pain and the course of the postoperative period among gynecological patients necessitates the use of the HADS scale in the preoperative period. Patients with symptoms of clinically pronounced preoperative anxiety should be prescribed counseling by a psychotherapist and anxiolytics at the preoperative examination stage. Conclusions. Prehospital anxiety level is a significant factor influencing the development of uncontrolled pain syndrome. The HADS scale identifies a "high risk" group for the development of uncontrolled pain in the postoperative period in patients awaiting uterine surgery and is a screening test.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>операции на матке</kwd><kwd>уровень боли</kwd><kwd>дооперационная тревожность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>uterine surgery</kwd><kwd>pain level</kwd><kwd>preoperative anxiety</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Авторы заявляют об отсутствии внешнего финансирования при проведении исследования.</funding-statement><funding-statement xml:lang="en">This study was not supported by any external sources of funding.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Weiser TG, Haynes AB, Molina G et al. 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