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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urmj</journal-id><journal-title-group><journal-title xml:lang="ru">Уральский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Ural Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-4389</issn><publisher><publisher-name>Ural State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52420/umj.23.5.18</article-id><article-id custom-type="edn" pub-id-type="custom">BZIWRW</article-id><article-id custom-type="elpub" pub-id-type="custom">urmj-1600</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные статьи | Original articles</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original articles</subject></subj-group></article-categories><title-group><article-title>Интегральная оценка степени тяжести родильниц с септическими осложнениями после критических акушерских состояний</article-title><trans-title-group xml:lang="en"><trans-title>An Integral Assessment of Patient’s Condition in Postpartum Women with Critic Obstetric Complications</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0895-4066</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лазарева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lazareva</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оксана Вячеславовна Лазарева — кандидат медицинских наук, доцент кафедры акушерства и гинекологии № 2</p><p>Омск</p></bio><bio xml:lang="en"><p>Oksana V. Lazareva - Candidate of Sciences (Medicine), Associate Professor of the Department of Obstetrics and Gynecology No. 2</p><p>Omsk</p></bio><email xlink:type="simple">lazow@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6113-8498</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шифман</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shifman</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефим Муневич Шифман — доктор медицинских наук, профессор, профессор кафедры анестезиологии и реаниматологии; профессор кафедры анестезиологии и реаниматологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Efim M. Shifman - Doctor of Sciences (Medicine), Professor, Professor of the Department of Anesthesiology and Intensive Care, Moscow Regional Research and Clinical Institute; Professor of the Department of Anesthesiology and Intensive Care</p><p>Moscow</p></bio><email xlink:type="simple">eshifman@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0357-7097</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баринов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Barinov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Владимирович Баринов — доктор медицинских наук, профессор, заведующий кафедрой акушерства и гинекологии № 2</p><p>Омск</p></bio><bio xml:lang="en"><p>Sergey V. Barinov - Doctor of Sciences (Medicine), Professor, Head of the Department of Obstetrics and Gynecology No. 2</p><p>Omsk</p></bio><email xlink:type="simple">barinov_omsk@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6080-1828</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шкабарня</surname><given-names>Л. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Sckabarnya</surname><given-names>L. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Людмила Леонидовна Шкабарня — заведующий отделением гинекологии</p><p>Москва</p><p>Омск</p></bio><bio xml:lang="en"><p>Lyudmila L. Sckabarnya - Head of the Department of Gynecology, Regional Clinical Hospital</p><p>Omsk</p></bio><email xlink:type="simple">l_shka@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-2602-2336</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Толкач</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Tolkach</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алла Борисовна Толкач — доктор медицинских наук, заведующий отделением реанимации и интенсивной терапии</p><p>Омск</p></bio><bio xml:lang="en"><p>lla B. Tolkach — Doctor of Sciences (Medicine), Head of the Department of Anesthesiology and Intensive Care</p><p>Omsk</p></bio><email xlink:type="simple">tolkach_omsk@rambler.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-8107-8819</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Носкова</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Noskova</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталья Митрофановна Носкова — руководитель лаборатории экспресс-диагностики лабораторного отделения</p><p>Омск</p></bio><bio xml:lang="en"><p>Natalia M. Noskova - Head of the Laboratory of Express Diagnostics of the Laboratory Department</p><p>Moscow</p></bio><email xlink:type="simple">noskova0805@list.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-3609-184X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартынова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Martynova</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Викторовна Мартынова — врач лаборатории экспресс-диагностики лабораторного отделения</p><p>Омск</p></bio><bio xml:lang="en"><p>Yulia V. Martynova - Physician of the Laboratory of Express Diagnostics of the Laboratory Department</p><p>Omsk</p></bio><email xlink:type="simple">yulia_1179@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5365-7119</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тирская</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tirskaya</surname><given-names>Yu. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Игоревна Тирская — доктор медицинских наук, профессор кафедры акушерства и гинекологии № 2</p><p>Омск</p></bio><bio xml:lang="en"><p>Yulia I. Tirskaya - Doctor of Sciences (Medicine), Professor of the Department of Obstetrics and Gynecology No. 2</p><p>Omsk</p></bio><email xlink:type="simple">yulia.tirskaya@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0348-5985</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кадцына</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kadtsyna</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татьяна Владимировна Кадцына — кандидат медицинских наук, доцент кафедры акушерства и гинекологии № 2</p><p>Омск</p></bio><bio xml:lang="en"><p>Tatyana V. Kadtsyna - Candidate of Sciences (Medicine), Associate Professor of the Department of Obstetrics and Gynecology No. 2</p><p>Omsk</p></bio><email xlink:type="simple">tatianavlad@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4806-6880</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чуловский</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Chulovskij</surname><given-names>J. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрий Игоревич Чуловский — кандидат медицинских наук, доцент кафедры акушерства и гинекологии № 2</p><p>Омск</p></bio><bio xml:lang="en"><p>Jurij I. Chulovskij - Candidate of Sciences (Medicine), Associate Professor of the Department of Obstetricsand Gynecology No. 2</p><p>Omsk</p></bio><email xlink:type="simple">akusheromsk@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Омский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский областной научно‑исследовательский клинический институт имени М. Ф. Владимирского; Российский национальный исследовательский медицинский университет имени Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research and Clinical Institute; N. I. Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Областная клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Областная клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N. I. Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>16</day><month>10</month><year>2024</year></pub-date><volume>23</volume><issue>5</issue><elocation-id>18–31</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Лазарева О.В., Шифман Е.М., Баринов С.В., Шкабарня Л.Л., Толкач А.Б., Носкова Н.М., Мартынова Ю.В., Тирская Ю.И., Кадцына Т.В., Чуловский Ю.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Лазарева О.В., Шифман Е.М., Баринов С.В., Шкабарня Л.Л., Толкач А.Б., Носкова Н.М., Мартынова Ю.В., Тирская Ю.И., Кадцына Т.В., Чуловский Ю.И.</copyright-holder><copyright-holder xml:lang="en">Lazareva O.V., Shifman E.M., Barinov S.V., Sckabarnya L.L., Tolkach A.B., Noskova N.M., Martynova Y.V., Tirskaya Y.I., Kadtsyna T.V., Chulovskij J.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.umjusmu.ru/jour/article/view/1600">https://www.umjusmu.ru/jour/article/view/1600</self-uri><abstract><p>Введение. Септические осложнения после критических акушерских состояний (КАС) являются актуальной проблемой акушерства.Цель работы - провести интегральную оценку степени тяжести родильниц с септическими осложнениями после КАС.Материалы и методы. Обследовано 39 родильниц после КАС (массивного акушерского кровотечения, тяжелой преэклампсии). Пациентки разделены на 2 группы: с присоединившимися септическими осложнениями (основная, n = 18) и без них (сравнения, n = 21).Результаты. Массивное акушерское кровотечение осложнилось геморрагическим шоком более чем у 75 % пациенток обеих групп. Преждевременная отслойка нормально расположенной плаценты статистически значимо чаще регистрировалась в основной группе (р = 0,04). Всем пациенткам выполнена тотальная гистерэктомия во время родов или в раннем послеродовом периоде. Синдром полиорганной недостаточности (ПОН) имел место у всех женщин основной группы и у 17/21 (80,95 %) в группе сравнения (р = 0,05). При оценке состояния родильниц с использованием интегральных шкал при поступлении в основной группе отмечалось большее количество баллов по шкалам APACHE II (р = 0,02), SOFA (р = 0,001), NEWS2 (р &lt; 0,001).В этой же группе септические осложнения развивались на 9 [4; 9] сутки после родоразрешения.Заключение. Факторами риска развития септических осложнений после КАС являются: ПОН, почечная недостаточность, острое повреждение почек, сердечная недостаточностью, респираторный дистресс-синдром, пневмония. У родильниц с риском септических осложнений после КАС изначально отмечается увеличение количество баллов по APACHE II, SOFA, NEWS2.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. Septic complications after critical obstetric conditions (COC) are a pressing problem in obstetrics. The aim of the study is to conduct an integral assessment of the severity of postpartum women with septic complications after COC.Materials and methods. We examined 39 postpartum women after COC (massive obstetric hemorrhage, severe preeclampsia). All patients were divided into 2 groups: the main group (n = 18) — with associated septic complications, the comparison group (n = 21) — without septic complications. The average age of the subjects was (29.80±6.48) years.Results. Obstetric bleeding was complicated by hemorrhagic shock in more than 75 % of patients in both groups. Premature detachment of a normally located placenta (PDNLP) was statistically significantly more often recorded in the main group (p = 0.04). All patients underwent total hysterectomy during childbirth or in the early postpartum period. Multiple organ failure syndrome (MODS) occurred in all women of the main group and in 17/21 (80.95 %) in the comparison group (p = 0.05). When assessing the condition of maternity hospitals using integral scales, a higher number of points were noted in the main group on the APACHE II scale (p = 0.02), SOFA (p = 0.001), NEWS2 (p &lt; 0.001). In the main group, septic complications developed on the 9 [4; 9] day after delivery.Conclusion. Risk factors for septic complications after COC are: MODS, renal failure, acute kidney injury, heart failure, respiratory distress syndrome, pneumonia. Maternity hospitals at risk of septic complications after COC initially show an increase in the number of points according to APACHE II, SOFA, NEWS2.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>септические осложнения</kwd><kwd>послеродовый пе риод</kwd><kwd>критические акушерские состояния</kwd><kwd>родильницы</kwd><kwd>акушерские кровотечения</kwd><kwd>тяжелая преэклампсия</kwd><kwd>полиорганная недостаточность</kwd><kwd>интегральные шкалы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>septic complications</kwd><kwd>postpartum period</kwd><kwd>critical obstetric conditions</kwd><kwd>puerperium</kwd><kwd>obstetric bleeding</kwd><kwd>severe preeclampsia</kwd><kwd>multiple organ failure</kwd><kwd>integral scales</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ivannikov NYu, Mitichkin AE, Dimitrova VI, Slyusareva OA, Khlynova SA, Dobrokhotova YuE. 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