<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urmj</journal-id><journal-title-group><journal-title xml:lang="ru">Уральский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Ural Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-4389</issn><publisher><publisher-name>Ural State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52420/umj.23.6.91</article-id><article-id custom-type="edn" pub-id-type="custom">OIGYIA</article-id><article-id custom-type="elpub" pub-id-type="custom">urmj-1645</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Литературные обзоры | Literature reviews</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Literature reviews</subject></subj-group></article-categories><title-group><article-title>Реабилитация когнитивных функций в виртуальной среде: систематический обзор</article-title><trans-title-group xml:lang="en"><trans-title>Rehabilitation of Cognitive Functions in a Virtual Environment: A Systematic Review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-0262-7009</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Артём Александрович Кузнецов — студент института клинической медицины</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Artyom A. Kuznetsov — Specialist’s Degree Student of the Institute of Clinical Medicine</p><p>Ekaterinburg</p></bio><email xlink:type="simple">aleksandrkuznesov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7328-9894</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петренко</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrenko</surname><given-names>T. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимур Сергеевич Петренко — кандидат медицинских наук, доцент, доцент кафедры психиатрии, психотерапии и наркологии, руководитель отдела координации деятельности молодежных научных лабораторий</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Timur S. Petrenko — Candidate of Sciences (Medicine), Associate Professor, Associate Professor of the Department of Psychiatry, Psychotherapy and Narcology, Head of the Department for Coordinating the Activities of Youth Scientific Laboratories</p><p>Ekaterinburg</p></bio><email xlink:type="simple">ts.petrenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Уральский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>12</day><month>12</month><year>2024</year></pub-date><volume>23</volume><issue>6</issue><elocation-id>91–107</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Кузнецов А.А., Петренко Т.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Кузнецов А.А., Петренко Т.С.</copyright-holder><copyright-holder xml:lang="en">Kuznetsov A.A., Petrenko T.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.umjusmu.ru/jour/article/view/1645">https://www.umjusmu.ru/jour/article/view/1645</self-uri><abstract><sec><title>Введение</title><p>Введение. По данным ВОЗ, в современном мире наблюдается тенденция к повышению среднего возраста населения. Это, наряду с другими эпидемиологическими факторами, создает предпосылки к увеличению распространенности когнитивных нарушений. Таким образом, проблема ранней диагностики когнитивных расстройств в настоящее время является особенно актуальной.</p><p>Цель — анализ современного состояния проблемы применения технологий виртуальной реальности в сфере нейрореабилитации, а также оценка клинической эффективности реабилитации когнитивных способностей в виртуальной среде по сравнению с традиционными методами.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В базе данных PubMed с использованием ключевых слов найдено 245 публикаций. После отбора в итоговую выборку включено 25 публикаций по рассматриваемой теме.</p></sec><sec><title>Результаты</title><p>Результаты. При анализе публикаций выявлено, что традиционные методы когнитивной реабилитации воздействуют только на социально значимые компоненты интеллекта, упуская другие стороны когнитивных способностей. Несмотря на актуальность темы нейрореабилитации, в настоящее время существует только шесть программ для обучения и реабилитации когнитивных способностей. Однако даже существующие предложения являются компьютерной интерпретацией традиционных методов реабилитации. При этом разные исследования свидетельствуют о различной степени их клинической эффективности, что затрудняет постановку однозначного вывода.</p></sec><sec><title>Обсуждение</title><p>Обсуждение. Применение виртуальной реальности для реабилитации когнитивных способностей является перспективным направлением в современной восстановительной неврологии. Эта технология не только позволяет добиться полного погружения пациента в сам процесс реабилитации, но и открывает возможности проведения реабилитации в удаленном формате. Тот факт, что разные публикации сообщают о различном уровне клинической эффективности подобной методики, вызван малым числом исследований и различиями в исследуемых когортах и методологии исследований.</p></sec><sec><title>Заключение</title><p>Заключение. Выявлено, что проблема применения виртуальной реальности в сфере нейрореабилитации в настоящее время актуальна. Однако для оценки клинической эффективности таких методик необходимо большее число масштабных исследований.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. According to WHO, nowadays there is a tendency towards an increase in the average age of the population. This creates preconditions for the prevalence of cognitive impairment increase. So, the problem of cognitive disorders early diagnosis is currently relevant.</p><p>The aim of the study is to analyze the current state of virtual reality technologies using in the field of neurorehabilitation, and to evaluate the clinical effectiveness of rehabilitation of cognitive abilities in a virtual environment in comparison with traditional methods.</p></sec><sec><title>Material and methods</title><p>Material and methods. 245 publications were found in the PubMed database using keywords. After selection, 25 publications were included in the final sample.</p></sec><sec><title>Results</title><p>Results. During the publications analyzing, it was revealed that traditional methods of neurorehabilitation affect only socially significant components. Despite the topic relevance, there are only 6 programs for cognitive abilities rehabilitation. But, existing programs are a computer interpretation of traditional methods. However different studies indicate different clinical effectiveness degrees, which makes it difficult to draw a clear conclusion.</p></sec><sec><title>Discussion</title><p>Discussion. The use of virtual reality for the cognitive abilities rehabilitation is a promising direction in modern restorative neurology. Among other things VR opens up opportunities for mount rehabilitation in a remote format. Different clinical efficacy levels in different publications is due to the small number of studies and differences in the research methodology.</p></sec><sec><title>Conclusion</title><p>Conclusion. It has been revealed that the problem of using virtual reality in the field of neurorehabilitation is currently relevant. However, more studies are needed to assess the clinical effectiveness of such methods.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>когнитивные функции</kwd><kwd>двигательные функции</kwd><kwd>виртуальная реальность</kwd><kwd>дополненная реальность</kwd><kwd>смешанная реальность</kwd><kwd>технологии</kwd><kwd>реабилитация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cognitive functions</kwd><kwd>motor functions</kwd><kwd>virtual reality</kwd><kwd>augmented reality</kwd><kwd>mixed reality</kwd><kwd>technology</kwd><kwd>rehabilitation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Oh YB, Kim GW, Han KS, Won YH, Park SH, Seo JH, et al. Eﬃcacy of virtual reality combined with real instrument training for patients with stroke: A randomized controlled trial. Archives of Physical Medicine and Rehabilitation. 2019;100(8):1400–1408. DOI: https://doi.org/10.1016/j.apmr.2019.03.013.</mixed-citation><mixed-citation xml:lang="en">Oh YB, Kim GW, Han KS, Won YH, Park SH, Seo JH, et al. Eﬃcacy of virtual reality combined with real instrument training for patients with stroke: A randomized controlled trial. Archives of Physical Medicine and Rehabilitation. 2019;100(8):1400–1408. DOI: https://doi.org/10.1016/j.apmr.2019.03.013.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Putrino D. Telerehabilitation and emerging virtual reality approaches to stroke rehabilitation. Current Opinion in Neurology. 2014;27(6):631–636. DOI: https://doi.org/10.1097/WCO.0000000000000152.</mixed-citation><mixed-citation xml:lang="en">Putrino D. Telerehabilitation and emerging virtual reality approaches to stroke rehabilitation. Current Opinion in Neurology. 2014;27(6):631–636. DOI: https://doi.org/10.1097/WCO.0000000000000152.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Foley NC, Teasell RW, Bhogal SK, Doherty T, Speechley MR. The eﬃcacy of stroke rehabilitation: A qualitative review. Topicsin Stroke Rehabilitation. 2003;10(2):1–18. DOI: https://doi.org/10.1310/aqe1-pcw1-fw9k-m01g.</mixed-citation><mixed-citation xml:lang="en">Foley NC, Teasell RW, Bhogal SK, Doherty T, Speechley MR. The eﬃcacy of stroke rehabilitation: A qualitative review. Topicsin Stroke Rehabilitation. 2003;10(2):1–18. DOI: https://doi.org/10.1310/aqe1-pcw1-fw9k-m01g.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kim H, Jung J, Lee S. Therapeutic application of virtual reality in the rehabilitation of mild cognitive impairment: A systematic review and meta-analysis. Vision. 2022;6(4):68. DOI: https://doi.org/10.3390/vision6040068.</mixed-citation><mixed-citation xml:lang="en">Kim H, Jung J, Lee S. Therapeutic application of virtual reality in the rehabilitation of mild cognitive impairment: A systematic review and meta-analysis. Vision. 2022;6(4):68. DOI: https://doi.org/10.3390/vision6040068.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Khedr EM, Hamed SA, El-Shereef HK, Shawky OA, Mohamed KhA, Awad EM, et al. Cognitive impairment aﬅer cerebrovascular stroke: Relationship to vascular risk factors. Neuropsychiatric Disease and Treatment. 2009;5:103–116. DOI: https://doi.org/10.2147/ndt.s4184.</mixed-citation><mixed-citation xml:lang="en">Khedr EM, Hamed SA, El-Shereef HK, Shawky OA, Mohamed KhA, Awad EM, et al. Cognitive impairment aﬅer cerebrovascular stroke: Relationship to vascular risk factors. Neuropsychiatric Disease and Treatment. 2009;5:103–116. DOI: https://doi.org/10.2147/ndt.s4184.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Nichols-Larsen DS, Clark PC, Zeringue A, Greenspan A, Blanton S. Factors inﬂuencing stroke survivors’ quality of life during subacute recovery. Stroke. 2005;36(7):1480–1484. DOI: https://doi.org/10.1161/01.STR.0000170706.13595.4f.</mixed-citation><mixed-citation xml:lang="en">Nichols-Larsen DS, Clark PC, Zeringue A, Greenspan A, Blanton S. Factors inﬂuencing stroke survivors’ quality of life during subacute recovery. Stroke. 2005;36(7):1480–1484. DOI: https://doi.org/10.1161/01.STR.0000170706.13595.4f.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990– 2019: A systematic analysis for the Global Burden of Disease Study 2019. The Lancet Neurology. 2021; 20(10):795–820. DOI: https://doi.org/10.1016/S1474-4422(21)00252–0.</mixed-citation><mixed-citation xml:lang="en">GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990– 2019: A systematic analysis for the Global Burden of Disease Study 2019. The Lancet Neurology. 2021; 20(10):795–820. DOI: https://doi.org/10.1016/S1474-4422(21)00252–0.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Sokołowska B. Impact of virtual reality cognitive and motor exercises on brain health. International Journal of Environmental Research and Public Health. 2023;20(5):4150. DOI: https://doi.org/10.3390/ijerph20054150.</mixed-citation><mixed-citation xml:lang="en">Sokołowska B. Impact of virtual reality cognitive and motor exercises on brain health. International Journal of Environmental Research and Public Health. 2023;20(5):4150. DOI: https://doi.org/10.3390/ijerph20054150.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Maggio MG, Maresca G, De Luca R, Stagnitti MC, Porcari B, Ferrera MC, et al. The growing use of virtual reality in cognitive rehabilitation: Fact, fake or vision? A scoping review. Journal of the National Medical Association. 2019;111(4):457–463. DOI: https://doi.org/10.1016/j.jnma.2019.01.003.</mixed-citation><mixed-citation xml:lang="en">Maggio MG, Maresca G, De Luca R, Stagnitti MC, Porcari B, Ferrera MC, et al. The growing use of virtual reality in cognitive rehabilitation: Fact, fake or vision? A scoping review. Journal of the National Medical Association. 2019;111(4):457–463. DOI: https://doi.org/10.1016/j.jnma.2019.01.003.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bevilacqua R, Maranesi E, Riccardi GR, Di Donna V, Pelliccioni P, Luzi R, et al. Non-immersive virtual reality for rehabilitation of the older people: A systematic review into eﬃcacy and eﬀectiveness. Journal of Clinical Medicine. 2019;8(11):1882. DOI: https://doi.org/10.3390/jcm8111882.</mixed-citation><mixed-citation xml:lang="en">Bevilacqua R, Maranesi E, Riccardi GR, Di Donna V, Pelliccioni P, Luzi R, et al. Non-immersive virtual reality for rehabilitation of the older people: A systematic review into eﬃcacy and eﬀectiveness. Journal of Clinical Medicine. 2019;8(11):1882. DOI: https://doi.org/10.3390/jcm8111882.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Moreno A, Wall KJ, Thangavelu K, Craven L, Ward E, Dissanayaka NN. A systematic review of the use of virtual reality and its eﬀects on cognition in individuals with neurocognitive disorders. Alzheimer’s &amp; Dementia: Translational Research &amp; Clinical Interventions. 2019;5(1):834–850. DOI: https://doi.org/10.1016/j.trci.2019.09.016.</mixed-citation><mixed-citation xml:lang="en">Moreno A, Wall KJ, Thangavelu K, Craven L, Ward E, Dissanayaka NN. A systematic review of the use of virtual reality and its eﬀects on cognition in individuals with neurocognitive disorders. Alzheimer’s &amp; Dementia: Translational Research &amp; Clinical Interventions. 2019;5(1):834–850. DOI: https://doi.org/10.1016/j.trci.2019.09.016.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Fratiglioni L, De Ronchi D, Agüero-Torres H. Worldwide prevalence and incidence of dementia. Drugs &amp; Aging. 1999;15(5):365–375. DOI: https://doi.org/10.2165/00002512-199915050-00004.</mixed-citation><mixed-citation xml:lang="en">Fratiglioni L, De Ronchi D, Agüero-Torres H. Worldwide prevalence and incidence of dementia. Drugs &amp; Aging. 1999;15(5):365–375. DOI: https://doi.org/10.2165/00002512-199915050-00004.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Liu Y, Tan W, Chen C, Liu C, Yang J, Zhang Y. A review of the application of virtual reality technology in the diagnosis and treatment of cognitive impairment. Frontiers in Aging Neuroscience. 2019;11:280. DOI: https://doi.org/10.3389/fnagi.2019.00280.</mixed-citation><mixed-citation xml:lang="en">Liu Y, Tan W, Chen C, Liu C, Yang J, Zhang Y. A review of the application of virtual reality technology in the diagnosis and treatment of cognitive impairment. Frontiers in Aging Neuroscience. 2019;11:280. DOI: https://doi.org/10.3389/fnagi.2019.00280.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Laver KE, Lange B, George S, Deutsch JE, Saposnik G, Crotty M. Virtual reality for stroke rehabilitation. Cochrane Database of Systematic Reviews. 2017;(11):CD008349. DOI: https://doi.org/10.1002/14651858.CD008349.pub4.</mixed-citation><mixed-citation xml:lang="en">Laver KE, Lange B, George S, Deutsch JE, Saposnik G, Crotty M. Virtual reality for stroke rehabilitation. Cochrane Database of Systematic Reviews. 2017;(11):CD008349. DOI: https://doi.org/10.1002/14651858.CD008349.pub4.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Held JP, Ferrer B, Mainetti R, Steblin A, Hertler B, Moreno-Conde A, et al. Autonomous rehabilitation at stroke patients home for balance and gait: Safety, usability and compliance of a virtual reality system. European Journal of Physical and Rehabilitation Medicine. 2018;54(4):545–553. DOI: https://doi.org/10.23736/S1973-9087.17.04802-X.</mixed-citation><mixed-citation xml:lang="en">Held JP, Ferrer B, Mainetti R, Steblin A, Hertler B, Moreno-Conde A, et al. Autonomous rehabilitation at stroke patients home for balance and gait: Safety, usability and compliance of a virtual reality system. European Journal of Physical and Rehabilitation Medicine. 2018;54(4):545–553. DOI: https://doi.org/10.23736/S1973-9087.17.04802-X.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Faria AL, Andrade A, Soares L, I Badia SB. Beneﬁts of virtual reality based cognitive rehabilitation through simulated activities of daily living: A randomized controlled trial with stroke patients. Journal of NeuroEngineering and Rehabilitation. 2016;13(1):96. DOI: https://doi.org/10.1186/s12984-016-0204-z.</mixed-citation><mixed-citation xml:lang="en">Faria AL, Andrade A, Soares L, I Badia SB. Beneﬁts of virtual reality based cognitive rehabilitation through simulated activities of daily living: A randomized controlled trial with stroke patients. Journal of NeuroEngineering and Rehabilitation. 2016;13(1):96. DOI: https://doi.org/10.1186/s12984-016-0204-z.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Lloréns R, Noé E, Colomer C, Alcañiz M. Eﬀectiveness, usability, and cost-beneﬁt of a virtual reality-based telerehabilitation program for balance recovery aﬅer stroke: A randomized controlled trial. Archives of Physical Medicine and Rehabilitation. 2015;96(3):418–425.e2. DOI: https://doi.org/10.1016/j.apmr.2014.10.019.</mixed-citation><mixed-citation xml:lang="en">Lloréns R, Noé E, Colomer C, Alcañiz M. Eﬀectiveness, usability, and cost-beneﬁt of a virtual reality-based telerehabilitation program for balance recovery aﬅer stroke: A randomized controlled trial. Archives of Physical Medicine and Rehabilitation. 2015;96(3):418–425.e2. DOI: https://doi.org/10.1016/j.apmr.2014.10.019.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Bauer ACM, Andringa G. The potential of immersive virtual reality for cognitive training in elderly. Gerontology. 2020;66(6):614–623. DOI: https://doi.org/10.1159/000509830.</mixed-citation><mixed-citation xml:lang="en">Bauer ACM, Andringa G. The potential of immersive virtual reality for cognitive training in elderly. Gerontology. 2020;66(6):614–623. DOI: https://doi.org/10.1159/000509830.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Allain P, Foloppe DA, Besnard J, Yamaguchi T, Etcharry-Bouyx F, Le Gall D, et al. Detecting everyday action deﬁcits in Alzheimer’s disease using a nonimmersive virtual reality kitchen. Journal of the International Neuropsychological Society. 2014;20(5):468–477. DOI: https://doi.org/10.1017/S1355617714000344.</mixed-citation><mixed-citation xml:lang="en">Allain P, Foloppe DA, Besnard J, Yamaguchi T, Etcharry-Bouyx F, Le Gall D, et al. Detecting everyday action deﬁcits in Alzheimer’s disease using a nonimmersive virtual reality kitchen. Journal of the International Neuropsychological Society. 2014;20(5):468–477. DOI: https://doi.org/10.1017/S1355617714000344.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Anguera JA, Boccanfuso J, Rintoul JL, Al-Hashimi O, Faraji F, Janowich J, et al. Video game training enhances cognitive control in older adults. Nature. 2013;501(7465):97–101. DOI: https://doi.org/10.1038/nature12486.</mixed-citation><mixed-citation xml:lang="en">Anguera JA, Boccanfuso J, Rintoul JL, Al-Hashimi O, Faraji F, Janowich J, et al. Video game training enhances cognitive control in older adults. Nature. 2013;501(7465):97–101. DOI: https://doi.org/10.1038/nature12486.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Gatica-Rojas V, Méndez-Rebolledo G. Virtual reality interface devicesin the reorganization of neural networks in the brain of patients with neurological diseases. Neural Regeneration Research. 2014;9(8):888–896. DOI: https://doi.org/10.4103/1673-5374.131612.</mixed-citation><mixed-citation xml:lang="en">Gatica-Rojas V, Méndez-Rebolledo G. Virtual reality interface devicesin the reorganization of neural networks in the brain of patients with neurological diseases. Neural Regeneration Research. 2014;9(8):888–896. DOI: https://doi.org/10.4103/1673-5374.131612.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Maggio MG, Naro A, La Rosa G, Cambria A, Lauria P, Billeri L, et al. Virtual reality based cognitive rehabilitation in minimally conscious state: A case report with EEG ﬁndings and systematic literature review. Brain Sciences. 2020;10(7):414. DOI: https://doi.org/10.3390/brainsci10070414.</mixed-citation><mixed-citation xml:lang="en">Maggio MG, Naro A, La Rosa G, Cambria A, Lauria P, Billeri L, et al. Virtual reality based cognitive rehabilitation in minimally conscious state: A case report with EEG ﬁndings and systematic literature review. Brain Sciences. 2020;10(7):414. DOI: https://doi.org/10.3390/brainsci10070414.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Kober SE, Schweiger D, Witte M, Reichert JL, Grieshofer P, Neuper Ch, et al. Speciﬁc eﬀects of EEG based neurofeedback training on memory functions in post-stroke victims. Journal of NeuroEngineering and Rehabilitation. 2015;12:107. DOI: https://doi.org/10.1186/s12984-015-0105-6.</mixed-citation><mixed-citation xml:lang="en">Kober SE, Schweiger D, Witte M, Reichert JL, Grieshofer P, Neuper Ch, et al. Speciﬁc eﬀects of EEG based neurofeedback training on memory functions in post-stroke victims. Journal of NeuroEngineering and Rehabilitation. 2015;12:107. DOI: https://doi.org/10.1186/s12984-015-0105-6.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Gibson RM, Owen AM, Cruse D. Brain-computer interfaces for patients with disorders of consciousness. Progress in Brain Research. 2016;228:241–291. DOI: https://doi.org/10.1016/bs.pbr.2016.04.003.</mixed-citation><mixed-citation xml:lang="en">Gibson RM, Owen AM, Cruse D. Brain-computer interfaces for patients with disorders of consciousness. Progress in Brain Research. 2016;228:241–291. DOI: https://doi.org/10.1016/bs.pbr.2016.04.003.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Shakhparonova NV, Kadykov AS. An algorithm for the diagnosis and treatment of memory disorders in neurological practice. Nervous Diseases. 2009;(1):13–16. (In Russ.). EDN: https://www.elibrary.ru/uypffb.</mixed-citation><mixed-citation xml:lang="en">Shakhparonova NV, Kadykov AS. An algorithm for the diagnosis and treatment of memory disorders in neurological practice. Nervous Diseases. 2009;(1):13–16. (In Russ.). EDN: https://www.elibrary.ru/uypffb.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Lima RR, Rose ML, Lima HN, Cabral NL, Silveira NC, Massi GA. Prevalence of aphasia aﬅer stroke in a hospital population in southern Brazil: A retrospective cohort study. Topicsin Stroke Rehabilitation. 2020; 27(3):215–223. DOI: https://doi.org/10.1080/10749357.2019.1673593.</mixed-citation><mixed-citation xml:lang="en">Lima RR, Rose ML, Lima HN, Cabral NL, Silveira NC, Massi GA. Prevalence of aphasia aﬅer stroke in a hospital population in southern Brazil: A retrospective cohort study. Topicsin Stroke Rehabilitation. 2020; 27(3):215–223. DOI: https://doi.org/10.1080/10749357.2019.1673593.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Malone LA, Sun LR. Transcranial magnetic stimulation for the treatment of pediatric neurological disorders. Current Treatment Options in Neurology. 2019;21(11):58. DOI: https://doi.org/10.1007/s11940-019-0600-3.</mixed-citation><mixed-citation xml:lang="en">Malone LA, Sun LR. Transcranial magnetic stimulation for the treatment of pediatric neurological disorders. Current Treatment Options in Neurology. 2019;21(11):58. DOI: https://doi.org/10.1007/s11940-019-0600-3.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Nesterova JV, Karkashadze GA, Yatsik LM, Namazova-Baranova LS, Vishneva EA, Kaytukova EV, et al. Management of children with speech disorders via transcranial magnetic stimulation: Non-randomized controlled study. Pediatric Pharmacology. 2022;19 (5):380–393. (In Russ.). DOI: https://doi.org/10.15690/pf.v19i5.2466.</mixed-citation><mixed-citation xml:lang="en">Nesterova JV, Karkashadze GA, Yatsik LM, Namazova-Baranova LS, Vishneva EA, Kaytukova EV, et al. Management of children with speech disorders via transcranial magnetic stimulation: Non-randomized controlled study. Pediatric Pharmacology. 2022;19 (5):380–393. (In Russ.). DOI: https://doi.org/10.15690/pf.v19i5.2466.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Mozheyko EYu. Recovery of speech disorders in poststroke patients: The urgency, problems and prospects. Siberian Medical Review. 2008;(2):16–20. (In Russ.). EDN: https://www.elibrary.ru/jvmjej.</mixed-citation><mixed-citation xml:lang="en">Mozheyko EYu. Recovery of speech disorders in poststroke patients: The urgency, problems and prospects. Siberian Medical Review. 2008;(2):16–20. (In Russ.). EDN: https://www.elibrary.ru/jvmjej.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Goncharova OV, Nikonova LS, Monakhov MV, Khan MA, Achkasov EE, The health status and principles of treatment for children with attention deﬁcit hyperactivity disorder. Bulletin of Rehabilitation Medicine. 2012;(2):45–49. (In Russ.). EDN: https://www.elibrary.ru/pabhgp.</mixed-citation><mixed-citation xml:lang="en">Goncharova OV, Nikonova LS, Monakhov MV, Khan MA, Achkasov EE, The health status and principles of treatment for children with attention deﬁcit hyperactivity disorder. Bulletin of Rehabilitation Medicine. 2012;(2):45–49. (In Russ.). EDN: https://www.elibrary.ru/pabhgp.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Wu J, Ma Y, Ren Z. Rehabilitative eﬀects of virtual reality technology for mild cognitive impairment: A systematic review with meta-analysis. Frontiers in Psychology. 2020;11:1811. DOI: https://doi.org/10.3389/fpsyg.2020.01811.</mixed-citation><mixed-citation xml:lang="en">Wu J, Ma Y, Ren Z. Rehabilitative eﬀects of virtual reality technology for mild cognitive impairment: A systematic review with meta-analysis. Frontiers in Psychology. 2020;11:1811. DOI: https://doi.org/10.3389/fpsyg.2020.01811.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Hattabi S, Bouallegue M, Ben Yahya H, Bouden A. Rehabilitation of ADHD children by sport intervention: A Tunisian experience. La Tunisie Médicale. 2019;97(7):874–881. PMID: https://pubmed.gov/31872398.</mixed-citation><mixed-citation xml:lang="en">Hattabi S, Bouallegue M, Ben Yahya H, Bouden A. Rehabilitation of ADHD children by sport intervention: A Tunisian experience. La Tunisie Médicale. 2019;97(7):874–881. PMID: https://pubmed.gov/31872398.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Calabrò RS, Naro A, Russo M, Leo A, De Luca R, Balletta T, et al. The role of virtual reality in improving motor performance as revealed by EEG: A randomized clinical trial. Journal of NeuroEngineering and Rehabilitation. 2017;14(1):53. DOI: https://doi.org/10.1186/s12984-017-0268-4.</mixed-citation><mixed-citation xml:lang="en">Calabrò RS, Naro A, Russo M, Leo A, De Luca R, Balletta T, et al. The role of virtual reality in improving motor performance as revealed by EEG: A randomized clinical trial. Journal of NeuroEngineering and Rehabilitation. 2017;14(1):53. DOI: https://doi.org/10.1186/s12984-017-0268-4.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Calabrò RS, Naro A, CiminoV, Buda A, Paladina G, Di Lorenzo G, et al. Improving motor performancein Parkinson’s disease: A preliminary study on the promising use of the computer assistedvirtual reality environment (CAREN). Neurological Sciences. 2020;41(4):933–941. DOI: https://doi.org/10.1007/s10072-019-04194-7.</mixed-citation><mixed-citation xml:lang="en">Calabrò RS, Naro A, CiminoV, Buda A, Paladina G, Di Lorenzo G, et al. Improving motor performancein Parkinson’s disease: A preliminary study on the promising use of the computer assistedvirtual reality environment (CAREN). Neurological Sciences. 2020;41(4):933–941. DOI: https://doi.org/10.1007/s10072-019-04194-7.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Dockx K, Bekkers EM, Van den Bergh V, Ginis P, Rochester L, Hausdorﬀ JM, et al. Virtual reality for rehabilitation in Parkinson’s disease. Cochrane Database of Systematic Reviews. 2016;(12):CD010760. DOI: https://doi.org/10.1002/14651858.CD010760.pub2.</mixed-citation><mixed-citation xml:lang="en">Dockx K, Bekkers EM, Van den Bergh V, Ginis P, Rochester L, Hausdorﬀ JM, et al. Virtual reality for rehabilitation in Parkinson’s disease. Cochrane Database of Systematic Reviews. 2016;(12):CD010760. DOI: https://doi.org/10.1002/14651858.CD010760.pub2.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Yang WC, Wang HK, Wu RM, Lo CS, Lin KH. Home-based virtual reality balance training and conventional balance training in Parkinson’s disease: A randomized controlled trial. Journal of the Formosan Medical Association. 2016;115(9):734–743. DOI: https://doi.org/10.1016/j.jfma.2015.07.012.</mixed-citation><mixed-citation xml:lang="en">Yang WC, Wang HK, Wu RM, Lo CS, Lin KH. Home-based virtual reality balance training and conventional balance training in Parkinson’s disease: A randomized controlled trial. Journal of the Formosan Medical Association. 2016;115(9):734–743. DOI: https://doi.org/10.1016/j.jfma.2015.07.012.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Lei C, Sunzi K, Dai F, Liu X, Wang Y, Zhang B, et al. Eﬀects of virtual reality rehabilitation training on gait and balance in patients with Parkinson’s disease: A systematic review. PLoS One. 2019;14(11):e0224819. DOI: https://doi.org/10.1371/journal.pone.0224819.</mixed-citation><mixed-citation xml:lang="en">Lei C, Sunzi K, Dai F, Liu X, Wang Y, Zhang B, et al. Eﬀects of virtual reality rehabilitation training on gait and balance in patients with Parkinson’s disease: A systematic review. PLoS One. 2019;14(11):e0224819. DOI: https://doi.org/10.1371/journal.pone.0224819.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Iruthayarajah J, McIntyre A, Cotoi A, Macaluso S, Teasell R. The use of virtual reality for balance among individuals with chronic stroke: A systematic review and meta-analysis. Topics in Stroke Rehabilitation. 2017; 24(1):68–79. DOI: https://doi.org/10.1080/10749357.2016.1192361.</mixed-citation><mixed-citation xml:lang="en">Iruthayarajah J, McIntyre A, Cotoi A, Macaluso S, Teasell R. The use of virtual reality for balance among individuals with chronic stroke: A systematic review and meta-analysis. Topics in Stroke Rehabilitation. 2017; 24(1):68–79. DOI: https://doi.org/10.1080/10749357.2016.1192361.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Donath L, Rössler R, Faude O. Eﬀects of virtual reality training (exergaming) compared to alternative exercise training and passive control on standing balance and functional mobility in healthy community-dwelling seniors: A meta-analytical review. Sports Medicine. 2016;46(9):1293–1309. DOI: https://doi.org/10.1007/s40279-016-0485-1.</mixed-citation><mixed-citation xml:lang="en">Donath L, Rössler R, Faude O. Eﬀects of virtual reality training (exergaming) compared to alternative exercise training and passive control on standing balance and functional mobility in healthy community-dwelling seniors: A meta-analytical review. Sports Medicine. 2016;46(9):1293–1309. DOI: https://doi.org/10.1007/s40279-016-0485-1.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Lina C, Guoen C, Huidan W, Yingqing W, Ying C, Xiaochun C, et al. The eﬀect of virtual reality on the ability to perform activities of daily living, balance during gait, and motor function in parkinson disease patients: A systematic review and meta-analysis. American Journal of Physical Medicine &amp; Rehabilitation. 2020; 99(10):917–924. DOI: https://doi.org/10.1097/PHM.0000000000001447.</mixed-citation><mixed-citation xml:lang="en">Lina C, Guoen C, Huidan W, Yingqing W, Ying C, Xiaochun C, et al. The eﬀect of virtual reality on the ability to perform activities of daily living, balance during gait, and motor function in parkinson disease patients: A systematic review and meta-analysis. American Journal of Physical Medicine &amp; Rehabilitation. 2020; 99(10):917–924. DOI: https://doi.org/10.1097/PHM.0000000000001447.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Anwar N, Karimi H, Ahmad A, Mumtaz N, Saqulain G, Gilani SA. A novel virtual reality training strategy for poststroke patients: A randomized clinical trial. Journal of Healthcare Engineering. 2021;2021:6598726. DOI: https://doi.org/10.1155/2021/6598726.</mixed-citation><mixed-citation xml:lang="en">Anwar N, Karimi H, Ahmad A, Mumtaz N, Saqulain G, Gilani SA. A novel virtual reality training strategy for poststroke patients: A randomized clinical trial. Journal of Healthcare Engineering. 2021;2021:6598726. DOI: https://doi.org/10.1155/2021/6598726.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Lu Y, Ge Y, Chen W, Xing W, Wei L, Zhang C, et al. The eﬀectiveness of virtual reality for rehabilitation of Parkinson disease: An overview of systematic reviews with meta-analyses. Systematic Reviews. 2022; 11(1):50. DOI: https://doi.org/10.1186/s13643-022-01924-5.</mixed-citation><mixed-citation xml:lang="en">Lu Y, Ge Y, Chen W, Xing W, Wei L, Zhang C, et al. The eﬀectiveness of virtual reality for rehabilitation of Parkinson disease: An overview of systematic reviews with meta-analyses. Systematic Reviews. 2022; 11(1):50. DOI: https://doi.org/10.1186/s13643-022-01924-5.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Lloréns R, Colomer-Font C, Alcañiz M, Noé-Sebastián E. BioTrak virtual reality system: Eﬀectiveness and satisfaction analysis for balance rehabilitation in patients with brain injury. Neurología (English Edition). 2012;28(5):268–275. DOI: https://doi.org/10.1016/j.nrleng.2012.04.016.</mixed-citation><mixed-citation xml:lang="en">Lloréns R, Colomer-Font C, Alcañiz M, Noé-Sebastián E. BioTrak virtual reality system: Eﬀectiveness and satisfaction analysis for balance rehabilitation in patients with brain injury. Neurología (English Edition). 2012;28(5):268–275. DOI: https://doi.org/10.1016/j.nrleng.2012.04.016.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Chen X, Liu F, Lin S, Yu L, Lin R. Eﬀects of virtual reality rehabilitation training on cognitive function and activities of daily living of patients with poststroke cognitive impairment: A systematic review and meta-analysis. Archives of Physical Medicine and Rehabilitation. 2022;103(7):1422–1435. DOI: https://doi.org/10.1016/j.apmr.2022.03.012.</mixed-citation><mixed-citation xml:lang="en">Chen X, Liu F, Lin S, Yu L, Lin R. Eﬀects of virtual reality rehabilitation training on cognitive function and activities of daily living of patients with poststroke cognitive impairment: A systematic review and meta-analysis. Archives of Physical Medicine and Rehabilitation. 2022;103(7):1422–1435. DOI: https://doi.org/10.1016/j.apmr.2022.03.012.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Kang JM, Kim N, Lee SY, Woo SK, Park G, Yeon BK, et al. Eﬀect of cognitive training in fully immersive virtual reality on visuospatial function and frontal-occipital functional connectivity in predementia: Randomized controlled trial. Journal of Medical Internet Research. 2021;23(5):e24526. DOI: https://doi.org/10.2196/24526.</mixed-citation><mixed-citation xml:lang="en">Kang JM, Kim N, Lee SY, Woo SK, Park G, Yeon BK, et al. Eﬀect of cognitive training in fully immersive virtual reality on visuospatial function and frontal-occipital functional connectivity in predementia: Randomized controlled trial. Journal of Medical Internet Research. 2021;23(5):e24526. DOI: https://doi.org/10.2196/24526.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">So BP, Lai DK, Cheung DS, Lam WK, Cheung JC, Wong DW. Virtual reality-based immersive rehabilitation for cognitive- and behavioral-impairment-related eating disorders: A VREHAB framework scoping review. International Journal of Environmental Research and Public Health. 2022;19(10):5821. DOI: https://doi.org/10.3390/ijerph19105821.</mixed-citation><mixed-citation xml:lang="en">So BP, Lai DK, Cheung DS, Lam WK, Cheung JC, Wong DW. Virtual reality-based immersive rehabilitation for cognitive- and behavioral-impairment-related eating disorders: A VREHAB framework scoping review. International Journal of Environmental Research and Public Health. 2022;19(10):5821. DOI: https://doi.org/10.3390/ijerph19105821.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Lombardi J, McCahill MP. Enabling social dimensions of learning through a persistent, uniﬁed, massively multi-user, and self-organizing virtual environment. Proceedings. Second International Conference on Creating, Connecting and Collaborating through Computing, 2004. 2004:166–172. DOI: https://doi.org/10.1109/C5.2004.1314386.</mixed-citation><mixed-citation xml:lang="en">Lombardi J, McCahill MP. Enabling social dimensions of learning through a persistent, uniﬁed, massively multi-user, and self-organizing virtual environment. Proceedings. Second International Conference on Creating, Connecting and Collaborating through Computing, 2004. 2004:166–172. DOI: https://doi.org/10.1109/C5.2004.1314386.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Shahmoradi L, Rezayi S. Cognitive rehabilitation in people with autism spectrum disorder: A systematic review of emerging virtual reality-based approaches. Journal of NeuroEngineering and Rehabilitation. 2022; 19(1):91. DOI: https://doi.org/10.1186/s12984-022-01069-5.</mixed-citation><mixed-citation xml:lang="en">Shahmoradi L, Rezayi S. Cognitive rehabilitation in people with autism spectrum disorder: A systematic review of emerging virtual reality-based approaches. Journal of NeuroEngineering and Rehabilitation. 2022; 19(1):91. DOI: https://doi.org/10.1186/s12984-022-01069-5.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Romero-Ayuso D, Toledano-González A, Rodríguez-Martínez MdC, Arroyo-Castillo P, Triviño-Juárez JM, González P, et al. Eﬀectiveness of virtual reality-based interventions for children and adolescents with ADHD: A systematic review and meta-analysis. Children. 2021;8(2):70. DOI: https://doi.org/10.3390/children8020070.</mixed-citation><mixed-citation xml:lang="en">Romero-Ayuso D, Toledano-González A, Rodríguez-Martínez MdC, Arroyo-Castillo P, Triviño-Juárez JM, González P, et al. Eﬀectiveness of virtual reality-based interventions for children and adolescents with ADHD: A systematic review and meta-analysis. Children. 2021;8(2):70. DOI: https://doi.org/10.3390/children8020070.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Zhu S, Sui Y, Shen Y, Zhu Y, Ali N, Guo C, et al. Eﬀects of virtual reality intervention on cognition and motor function in older adults with mild cognitive impairment or dementia: A systematic review and meta-analysis. Frontiers in Aging Neuroscience. 2021;13:586999. DOI: https://doi.org/10.3389/fnagi.2021.586999.</mixed-citation><mixed-citation xml:lang="en">Zhu S, Sui Y, Shen Y, Zhu Y, Ali N, Guo C, et al. Eﬀects of virtual reality intervention on cognition and motor function in older adults with mild cognitive impairment or dementia: A systematic review and meta-analysis. Frontiers in Aging Neuroscience. 2021;13:586999. DOI: https://doi.org/10.3389/fnagi.2021.586999.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Chatterjee K, Buchanan A, Cottrell K, Hughes S, Day TW, John NW. Immersive virtual reality for the cognitive rehabilitation of stroke survivors. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 2022;30:719–728. DOI: https://doi.org/10.1109/TNSRE.2022.3158731.</mixed-citation><mixed-citation xml:lang="en">Chatterjee K, Buchanan A, Cottrell K, Hughes S, Day TW, John NW. Immersive virtual reality for the cognitive rehabilitation of stroke survivors. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 2022;30:719–728. DOI: https://doi.org/10.1109/TNSRE.2022.3158731.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Bourgeois A, Schnider A, Turri F, Ptak R. Virtual reality in the rehabilitation of cognitive impairment aﬅer stroke. Clinical and Translational Neuroscience. 2023;7(1):3. DOI: https://doi.org/10.3390/ctn7010003.</mixed-citation><mixed-citation xml:lang="en">Bourgeois A, Schnider A, Turri F, Ptak R. Virtual reality in the rehabilitation of cognitive impairment aﬅer stroke. Clinical and Translational Neuroscience. 2023;7(1):3. DOI: https://doi.org/10.3390/ctn7010003.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Faria AL, Andrade A, Soares L, I Badia SB. Beneﬁts of virtual reality based cognitive rehabilitation through simulated activities of daily living: A randomized controlled trial with stroke patients. Journal of NeuroEngineering and Rehabilitation. 2016;13(1):96. DOI: https://doi.org/10.1186/s12984-016-0204-z.</mixed-citation><mixed-citation xml:lang="en">Faria AL, Andrade A, Soares L, I Badia SB. Beneﬁts of virtual reality based cognitive rehabilitation through simulated activities of daily living: A randomized controlled trial with stroke patients. Journal of NeuroEngineering and Rehabilitation. 2016;13(1):96. DOI: https://doi.org/10.1186/s12984-016-0204-z.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Galperin I, Mirelman A, Schmitz-Hübsch T, Hsieh KL, Regev K, Karni A, et al. Treadmill training with virtual reality to enhance gait and cognitive function among people with multiple sclerosis: A randomized controlled trial. Journal of Neurology. 2023;270(3):1388–1401. DOI: https://doi.org/10.1007/s00415-022-11469-1.</mixed-citation><mixed-citation xml:lang="en">Galperin I, Mirelman A, Schmitz-Hübsch T, Hsieh KL, Regev K, Karni A, et al. Treadmill training with virtual reality to enhance gait and cognitive function among people with multiple sclerosis: A randomized controlled trial. Journal of Neurology. 2023;270(3):1388–1401. DOI: https://doi.org/10.1007/s00415-022-11469-1.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang Q, Fu Y, Lu Y. Impact of virtual reality-based therapies on cognition and mental health of stroke patients: Systematic review and meta-analysis. Journal of Medical Internet Research. 2021;23(11):e31007. DOI: https://doi.org/10.2196/31007.</mixed-citation><mixed-citation xml:lang="en">Zhang Q, Fu Y, Lu Y. Impact of virtual reality-based therapies on cognition and mental health of stroke patients: Systematic review and meta-analysis. Journal of Medical Internet Research. 2021;23(11):e31007. DOI: https://doi.org/10.2196/31007.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Georgiev DD, Georgieva I, Gong Z, Nanjappan V, Georgiev GV. Virtual reality for neurorehabilitation and cognitive enhancement. Brain Sciences. 2021;11(2):221. DOI: https://doi.org/10.3390/brainsci11020221.</mixed-citation><mixed-citation xml:lang="en">Georgiev DD, Georgieva I, Gong Z, Nanjappan V, Georgiev GV. Virtual reality for neurorehabilitation and cognitive enhancement. Brain Sciences. 2021;11(2):221. DOI: https://doi.org/10.3390/brainsci11020221.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Rogers JM, Duckworth J, Middleton S, Steenbergen B, Wilson PH. Elements virtual rehabilitation improves motor, cognitive, and functional outcomes in adult stroke: Evidence from a randomized controlled pilot study. Journal of NeuroEngineering and Rehabilitation. 2019;16(1):56. DOI: https://doi.org/10.1186/s12984–019–0531-y.</mixed-citation><mixed-citation xml:lang="en">Rogers JM, Duckworth J, Middleton S, Steenbergen B, Wilson PH. Elements virtual rehabilitation improves motor, cognitive, and functional outcomes in adult stroke: Evidence from a randomized controlled pilot study. Journal of NeuroEngineering and Rehabilitation. 2019;16(1):56. DOI: https://doi.org/10.1186/s12984–019–0531-y.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Vilageliu-Jordà E, Enseñat-Cantallops A, García-Molina A. Uso de la realidad virtual inmersiva en la rehabilitación cognitiva de pacientes con daño cerebral. Revisión sistemática [Use of immersive virtual reality for cognitive rehabilitation of patients with brain injury]. Revista de Neurología. 2022;74(10):331–339. DOI: https://doi.org/10.33588/rn.7410.2022034.</mixed-citation><mixed-citation xml:lang="en">Vilageliu-Jordà E, Enseñat-Cantallops A, García-Molina A. Uso de la realidad virtual inmersiva en la rehabilitación cognitiva de pacientes con daño cerebral. Revisión sistemática [Use of immersive virtual reality for cognitive rehabilitation of patients with brain injury]. Revista de Neurología. 2022;74(10):331–339. DOI: https://doi.org/10.33588/rn.7410.2022034.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Optale G, Urgesi C, Busato V, Marin S, Piron L, Priﬅis K, et al. Controlling memory impairment in elderly adults using virtual reality memory training: A randomized controlled pilot study. Neurorehabilitation and Neural Repair. 2010;24(4):348–357. DOI: https://doi.org/10.1177/1545968309353328.</mixed-citation><mixed-citation xml:lang="en">Optale G, Urgesi C, Busato V, Marin S, Piron L, Priﬅis K, et al. Controlling memory impairment in elderly adults using virtual reality memory training: A randomized controlled pilot study. Neurorehabilitation and Neural Repair. 2010;24(4):348–357. DOI: https://doi.org/10.1177/1545968309353328.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Yang HL, Chu H, Kao CC, Chiu HL, Tseng IJ, Tseng P, et al. Development and eﬀectiveness of virtual interactive working memory training for older people with mild cognitive impairment: A single-blind randomised controlled trial. Age Ageing. 2019;48(4):519–525. DOI: https://doi.org/10.1093/ageing/afz029.</mixed-citation><mixed-citation xml:lang="en">Yang HL, Chu H, Kao CC, Chiu HL, Tseng IJ, Tseng P, et al. Development and eﬀectiveness of virtual interactive working memory training for older people with mild cognitive impairment: A single-blind randomised controlled trial. Age Ageing. 2019;48(4):519–525. DOI: https://doi.org/10.1093/ageing/afz029.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
