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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urmj</journal-id><journal-title-group><journal-title xml:lang="ru">Уральский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Ural Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-4389</issn><publisher><publisher-name>Ural State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52420/umj.24.2.129</article-id><article-id custom-type="edn" pub-id-type="custom">OBPNTP</article-id><article-id custom-type="elpub" pub-id-type="custom">urmj-1783</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Литературные обзоры | Literature reviews</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Literature reviews</subject></subj-group></article-categories><title-group><article-title>Обзор профилактических мероприятий, направленных на повышение устойчивости организма к неблагоприятным воздействиям антропогенных и климатических факторов окружающей среды северных территорий России</article-title><trans-title-group xml:lang="en"><trans-title>Review of Preventive Measures Aimed at Increasing the Body Resistance to Adverse Effects of Anthropogenic and Climatic Factors of the Environment in the Northern Territories of Russia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-0780-5733</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никогосян</surname><given-names>К. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikogosyan</surname><given-names>K. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карен Мерсопович Никогосян — младший научный сотрудник отдела токсикологии и биопрофилактики.</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Karen M. Nikogosyan — Junior Researcher of the Department of Toxicology and Bioprophylaxis.</p><p>Ekaterinburg</p></bio><email xlink:type="simple">nikoghosyankm@ymrc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1743-7642</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сутункова</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Sutunkova</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марина Петровна Сутункова — доктор медицинских наук, директор, Екатеринбургский медицинский научный центр профилактики и охраны здоровья рабочих промпредприятий,; заведующий кафедрой гигиены и медицины труда, Уральский государственный медицинский университет.</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Marina P. Sutunkova — Doctor of Sciences (Medicine), Director, Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers; Head of the Department of Occupational Hygiene and Medicine, Ural SMU.</p><p>Ekaterinburg</p></bio><email xlink:type="simple">sutunkova@ymrc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2677-0479</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рябова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ryabova</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Владимировна Рябова — кандидат медицинских наук, заведующий лабораторией научных основ биологической профилактики.</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Yuliya V. Ryabova — Candidate of Sciences (Medicine), Head of the Laboratory of Scientific Foundations of Bioprophylaxis.</p><p>Ekaterinburg</p></bio><email xlink:type="simple">ryabova@ymrc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3960-6830</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мустафина</surname><given-names>И. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Mustafina</surname><given-names>I. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Илина Закарияновна Мустафина — кандидат медицинских наук, заведующий учебной частью.</p><p>Москва</p></bio><bio xml:lang="en"><p>Ilina Z. Mustafina — Candidate of Sciences (Medicine), Head of the Study Section.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1871-8593</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минигалиева</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Minigalieva</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ильзира Амировна Минигалиева — доктор биологических наук, заведующий отделом токсикологии и биопрофилактики.</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Ilzira A. Minigalieva — Doctor of Sciences (Biology), Head of the Department of Toxicology and Bioprophylaxis.</p><p>Ekaterinburg</p></bio><email xlink:type="simple">ilzira@ymrc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8566-2446</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мажаева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazhaeva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татьяна Васильевна Мажаева — кандидат медицинских наук, ведущий научный сотрудник, заведующая отделом гигиены питания, качества и безопасности продукции.</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Tatyana V. Mazhaeva — Candidate of Sciences (Medicine), Leading Researcher, Head of the Department of Nutrition Hygiene, Food Quality and Safety.</p><p>Ekaterinburg</p></bio><email xlink:type="simple">mazhaeva@ymrc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4694-0175</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Батенёва</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bateneva</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Влада Андреевна Батенёва — лаборант‑исследователь отдела токсикологии и биопрофилактики.</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Vlada A. Bateneva — Laboratory Technician and Researcher, Department of Toxicology and Bioprophylaxis.</p><p>Ekaterinburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8284-0008</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабардина</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabardina</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лада Владимировна Шабардина — младший научный сотрудник отдела токсикологии и биопрофилактики.</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Lada V. Shabardina — Junior Researcher of the Department of Toxicology and Bioprophylaxis.</p><p>Ekaterinburg</p></bio><email xlink:type="simple">lada.shabardina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Екатеринбургский медицинский научный центр профилактики и охраны здоровья рабочих промпредприятий</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Екатеринбургский медицинский научный центр профилактики и охраны здоровья рабочих промпредприятий; Уральский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers; Ural State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>05</day><month>05</month><year>2025</year></pub-date><volume>24</volume><issue>2</issue><elocation-id>129–146</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Никогосян К.М., Сутункова М.П., Рябова Ю.В., Мустафина И.З., Минигалиева И.А., Мажаева Т.В., Батенёва В.А., Шабардина Л.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Никогосян К.М., Сутункова М.П., Рябова Ю.В., Мустафина И.З., Минигалиева И.А., Мажаева Т.В., Батенёва В.А., Шабардина Л.В.</copyright-holder><copyright-holder xml:lang="en">Nikogosyan K.M., Sutunkova M.P., Ryabova Y.V., Mustafina I.Z., Minigalieva I.A., Mazhaeva T.V., Bateneva V.A., Shabardina L.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.umjusmu.ru/jour/article/view/1783">https://www.umjusmu.ru/jour/article/view/1783</self-uri><abstract><sec><title>Введение</title><p>Введение. Одномоментное воздействие неблагоприятных погодно-климатических условий и химических факторов среды повышает вероятность нарушения здоровья человека, которая зависит от индивидуальных особенностей организма и может быть управляема средствами специфической и неспецифической защиты. Одним из таких средств является биологическая профилактика, включающая в себя меры по повышению устойчивости организма и усилению адаптационных механизмов организма.</p><p>Цель — обобщение научных материалов об особенностях питания жителей северных территорий России для обоснования необходимости разработки профилактических мероприятий, направленных на повышение устойчивости организма к неблагоприятным воздействиям антропогенных и климатических факторов окружающей среды в условиях Крайнего Севера.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен библиографический поиск по информационным базам данных PubMed, Google Scholar, eLibrary.ru, «КиберЛенинка». Обнаружено более 100 оригинальных статей, в результате из них критериям включения соответствовала 61 полнотекстовая публикация, представленная в обзоре.</p></sec><sec><title>Результаты</title><p>Результаты. Постепенный переход на западный тип питания населения, проживающего на северных территориях, приводит к повышенному потреблению углеводов, недостаточному — жиров и белков. Зафиксирован дефицит йода, витаминов А, Е, С и D, причем последний усугубляется генетическим фактором у представителей коренных народов. Содержание тяжелых металлов, в частности свинца и ртути, в биосредах организма зачастую связано с геохимическими особенностями территории проживания и употреблением местной рыбы.</p></sec><sec><title>Заключение</title><p>Заключение. Для сохранения здоровья населения, проживающего на северных территориях России, необходима профилактическая стратегия, с одной стороны, направленная на обогащение витаминами и минералами пищевых рационов, с другой — повышающая устойчивость организма к вредному действию токсических агентов, которые могут присутствовать в традиционных пищевых продуктах.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Simultaneous exposure to unfavorable weather and climate conditions and environmental chemicals poses risks of human health impairment, realization of which depends on individual characteristics of the organism and can be controlled by biological prophylaxis comprising measures to increase the resistance and strengthen the adaptive mechanisms of the body.</p><p>Objective — to review the scientific experience of taking preventive measures aimed at increasing the body resistance to adverse effects of anthropogenic and climatic factors in the northern territories of Russia.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We conducted an electronic bibliography search in the PubMed, Google Scholar, eLibrary.ru, and CyberLeninka information databases. Of 100 original articles found, 61 full-text publications were eligible for inclusion in the review.</p></sec><sec><title>Results</title><p>Results. A gradual switchover to the Western pattern diet of the northerners leads to increased consumption of carbohydrates but insufficient intake of fats and proteins. The researchers have observed deficiency of iodine, vitamins A, E, C, and D, with the latter being aggravated by the genetic factor in indigenous peoples. Levels of heavy metals, particularly those of lead and mercury, in biological fluids are often associated with geochemical characteristics of the territory and local fish consumption.</p></sec><sec><title>Conclusion</title><p>Conclusion. To maintain health of the population living in the northern territories of Russia, it is important to develop a preventive strategy aimed, on the one hand, at enriching the diet with vitamins and minerals and, on the other hand, increasing the body resistance to adverse effects of toxicants potentially present in traditional foods.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>пищевой статус</kwd><kwd>дефицит</kwd><kwd>витамины</kwd><kwd>загрязнители среды обитания</kwd><kwd>токсические агенты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nutritional status</kwd><kwd>deficiency</kwd><kwd>vitamins</kwd><kwd>environmental pollutants</kwd><kwd>toxic agents</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Katsnelson BA, Morosova KI, Velichkovski BT, Aronova GV, Genkin AM, Rotenberg YS, et al. Anti-silikotische Wirkung von Glutamat. 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