urmjУральский медицинский журналUral Medical Journal2949-4389Ural State Medical University10.52420/umj.24.6.7AIJJJXurmj-2026Research ArticleОригинальные статьи | Original articlesOriginal articlesЛихорадка денге в Свердловской области: клинико-эпидемиологическая характеристика завозных случаевDengue Fever in the Sverdlovsk Region: Clinical and Epidemiological Characteristics of Imported Caseshttps://orcid.org/0009-0004-3231-9531УстюговаС. А.UstyugovaS. A.

Софья Александровна Устюгова – ассистент кафедры инфекционных болезней, фтизиатрии и пульмонологии, институт профилактической медицины

Екатеринбург

Sofya A. Ustyugova – Assistant of the Department of Infectious Diseases, Phthisiology and Pulmonology,Institute of Preventive Medicine

Ekaterinburg

https://orcid.org/0000-0003-0858-9529СабитовА. У.SabitovA. U.

Алебай Усманович Сабитов – доктор медицинских наук, профессор, заведующий кафедрой инфекционных болезней, фтизиатрии и пульмонологии, институт профилактической медицины

Екатеринбург

Alеbay U. Sabitov – Doctor of Sciences (Medicine), Professor, Head of the Department of Infectious Diseases, Phthisiology and Pulmonology, Institute of Preventive Medicine

Ekaterinburg

sabitov@yandex.ruhttps://orcid.org/0000-0001-9929-6531ХамановаЮ. Б.KhamanovaYu. B.

Юлия Борисовна Хаманова – доктор медицинских наук, доцент кафедры инфекционных болезней,фтизиатрии и пульмонологии, институт профилактической медицины

Екатеринбург

Yulia B. Khamanova – Doctor of Sciences (Medicine), Associate Professor of the Department of InfectiousDiseases, Phthisiology and Pulmonology, Institute of Preventive Medicine

Ekaterinburg

yngi@inbox.ruБабинцеваН. А.BabintsevaN. A.

Надежда Алексеевна Бабинцева – инфекционист инфекционного отделения № 1

Екатеринбург

Nadezhda A. Babintseva – Infectiologist of the Infectious Diseases Department № 1

Ekaterinburg

DimKB@mail.ruhttps://orcid.org/0000-0001-5613-126XБелоусовВ. В.BelousovV. V.

Виталий Витальевич Белоусов – ассистент кафедры инфекционных болезней, фтизиатрии и пульмонологии, институт профилактической медицины; инфекционист, заведующий инфекционным отделением № 1

Екатеринбург

Vitaly V. Belousov – Assistant of the Department of Infectious Diseases, Phthisiology and Pulmonology,Institute of Preventive Medicine; Infectiologist, Head of the Infectious Diseases Department № 1

Ekaterinburg

vitaLB@icloud.comhttps://orcid.org/0009-0001-9255-6254СолдатовД. А.SoldatovD. A.

Дмитрий Анатольевич Солдатов – кандидат медицинских наук, доцент кафедры инфекционных болезней, фтизиатрии и пульмонологии, институт профилактической медицины

Екатеринбург

Dmitry A. Soldatov – Candidate of Sciences (Medicine), Associate Professor of the Department of InfectiousDiseases, Phthisiology and Pulmonology, Institute of Preventive Medicine

Ekaterinburg

soldatoff.mitya2012@yandex.ruУральский государственный медицинский университетРоссияUral State Medical UniversityRussian FederationГородская клиническая больница № 40РоссияCity Clinical Hospital № 40Russian FederationУральский государственный медицинский университет; Городская клиническая больница № 40РоссияUral State Medical University; City Clinical Hospital № 40Russian Federation2025231220252467–18Copyright © Устюгова С.А., Сабитов А.У., Хаманова Ю.Б., Бабинцева Н.А., Белоусов В.В., Солдатов Д.А., 20252025Устюгова С.А., Сабитов А.У., Хаманова Ю.Б., Бабинцева Н.А., Белоусов В.В., Солдатов Д.А.Ustyugova S.A., Sabitov A.U., Khamanova Y.B., Babintseva N.A., Belousov V.V., Soldatov D.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.umjusmu.ru/jour/article/view/2026Введение

Введение. В России повышается распространение такой тропической инфекции, как лихорадке денге. Увеличение числа завозных случаев обусловлено общей неблагоприятной ситуацией по денге в мире, расширением ареала комара-переносчика и растущим туристическим потоком в эндемичные регионы. Повторное инфицирование разными серотипами вируса может привести к тяжелому течению болезни с проявлениями шока и геморрагического синдрома. С учетом этого возрастает риск развития тяжелой денге у туристов, многократно посещающих эндемичные страны.

Цель исследования – охарактеризовать эпидемиологические и клинические особенности завозных случаев лихорадки денге в Свердловской области для повышения настороженности медицинских работников в отношении этой инфекции.

Материалы и методы

Материалы и методы. Произведен ретроспективный анализ 13 случаев лихорадки денге на базе инфекционного корпуса Городской клинической больницы № 40 (Екатеринбург).

Результаты

Результаты. Случаи лихорадки денге в Свердловской области протекают в среднетяжелой форме болезни, однако у части пациентов отмечены предупреждающие признаки: кровоточивость, геморрагическая сыпь, умеренно выраженная тромбоцитопения. Лабораторное подтверждение получено у 11/13 пациентов (84,62 %): у четверых в иммуноферментном анализе обнаружены антитела класса G в пределах 7 дней от начала болезни, что может указывать на реинфекцию.

Introduction

Introduction. The spread of such a tropical infection as dengue fever (DF) is increasing in Russia. The increase in the number of imported cases is due to the general unfavorable situation of dengue in the world, the expansion of the range of the mosquito vector and the growing tourist flow to endemic regions. Repeated infection with different serotypes of the virus can lead to a severe course of the disease with manifestations of shock and hemorrhagic syndrome. Given this, the risk of developing severe dengue increases among tourists who repeatedly visit endemic countries.

Purpose of the study is to characterize the epidemiological and clinical features of imported cases of DF in the Sverdlovsk Region with a Sensor for increasing alertness regarding the current infection.

Materials and methods

Materials and methods. A retrospective analysis of 13 cases of DF was performed on the basis of the City Clinical Hospital No. 40 in Ekaterinburg. Statistical data processing was carried out with the calculation of median, upper and lower quartiles, Mann-Whitney criterion, Spearman correlation coefficient.

Results

Results. Cases of DF in the Sverdlovsk Region fit into the moderate form of the disease, however, a significant proportion of patients have warning signs: bleeding, hemorrhagic rash, moderate thrombocytopenia. Laboratory confirmation was obtained in 11/13 patients (84.62 %), four ELISA detected class G antibodies within 7 days of the onset of the disease, which may indicate reinfection.

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The authors declare that there are no conflicts of interest present.