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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urmj</journal-id><journal-title-group><journal-title xml:lang="ru">Уральский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Ural Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-4389</issn><publisher><publisher-name>Ural State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52420/umj.24.6.82</article-id><article-id custom-type="edn" pub-id-type="custom">HDYOVF</article-id><article-id custom-type="elpub" pub-id-type="custom">urmj-2036</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Литературные обзоры | Literature reviews</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Literature reviews</subject></subj-group></article-categories><title-group><article-title>Преэклампсия: медико-социальные риски и экономические последствия. Системный взгляд на акушерскую проблему XXI века</article-title><trans-title-group xml:lang="en"><trans-title>Preeclampsia: Medical and Social Risks and Economic Consequences. A Systematic View of the 21st Century Obstetric Problem</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6223-8888</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таскина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Taskina</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елизавета Сергеевна Таскина – кандидат медицинских наук, доцент кафедры офтальмологии; офтальмолог</p><p>Чита</p></bio><bio xml:lang="en"><p>Elizaveta S. Taskina – Candidate of Sciences (Medicine), Associate Professor of the Department of Ophthalmology; Ophthalmologist</p><p>Chita</p></bio><email xlink:type="simple">taskins@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5961-5400</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мудров</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mudrov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виктор Андреевич Мудров – доктор медицинских наук, доцент, профессор кафедры акушерства и гинекологии педиатрического факультета и факультета дополнительного профессионального образования; акушер-гинеколог</p><p>Чита</p></bio><bio xml:lang="en"><p>Victor A. Mudrov – Doctor of Sciences (Medicine), Associate Professor, Professor of the Department of Obstetrics and Gynecology of the Faculty of Pediatrics and the Faculty of Continuing Professional Education; Obstetrician-Gynecologist</p><p>Chita</p></bio><email xlink:type="simple">mudrov_viktor@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4390-183X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кибалина</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kibalina</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ирина Владимировна Кибалина – доктор медицинских наук, доцент, директор научно-исследовательского института молекулярной медицины, заведующий кафедрой нормальной физиологии имени профессора Б. И. Кузника</p><p>Чита</p></bio><bio xml:lang="en"><p>Irina V. Kibalina – Doctor of Sciences (Medicine), Associate Professor, Director of the Research Institute of Molecular Medicine, Head of the Department of Normal Physiology named after Professor B. I. Kuznik</p><p>Chita</p></bio><email xlink:type="simple">physiology_chgma@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-2661-5244</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агафонова</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Agafonova</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Николаевна Агафонова – главный врач</p><p>Чита</p></bio><bio xml:lang="en"><p>Elena N. Agafonova – Chief Physician</p><p>Chita</p></bio><email xlink:type="simple">priemnaya.zkpc@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-5968-2151</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Старицына</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Staritsyna</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ольга Анатольевна Старицына – заведующий отделением патологии беременных</p><p>Чита</p></bio><bio xml:lang="en"><p>Olga A. Staritsyna – Head of the Department of Pathology of Pregnant Women</p><p>Chita</p></bio><email xlink:type="simple">olgastaritzyna@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Читинская государственная медицинская академия; Забайкальский краевой перинатальный центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chita State Medical Academy; Zabaikalsky Regional Perinatal Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Читинская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chita State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Забайкальский краевой перинатальный центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Zabaikalsky Regional Perinatal Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2025</year></pub-date><volume>24</volume><issue>6</issue><elocation-id>82–102</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Таскина Е.С., Мудров В.А., Кибалина И.В., Агафонова Е.Н., Старицына О.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Таскина Е.С., Мудров В.А., Кибалина И.В., Агафонова Е.Н., Старицына О.А.</copyright-holder><copyright-holder xml:lang="en">Taskina E.S., Mudrov V.A., Kibalina I.V., Agafonova E.N., Staritsyna O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.umjusmu.ru/jour/article/view/2036">https://www.umjusmu.ru/jour/article/view/2036</self-uri><abstract><p>Преэклампсия – не просто акушерское осложнение, а системный кардиометаболический стресс-тест, раскрывающий скрытые риски для здоровья матери и ребенка на десятилетия вперед. Признанная одной из ведущих причин материнской и перинатальной смертности преэклампсия выходит далеко за рамки гестационного периода: она является мощным предиктором будущих заболеваний у женщины, а также фактором риска нарушений развития, метаболического синдрома и артериальной гипертензии у потомства. В настоящей работе представлен комплексный анализ факторов риска и патогенеза, клинических проявлений, современных подходов к профилактике и лечению, а также социально-экономического бремени преэклампсии для системы здравоохранения и общества. Особое внимание уделено формированию междисциплинарной модели ведения таких пациенток, включая принципы пожизненного диспансерного наблюдения. Преэклампсия требует переосмысления: от эпизодического акушерского вмешательства к стратегии долгосрочной охраны здоровья двух поколений. Это диктует необходимость тесного взаимодействия акушеров-гинекологов, кардиологов, неврологов, эндокринологов и терапевтов для формирования единой жизненной стратегии охраны здоровья женщины. Ее последствия носят системный и пролонгированный характер, что делает ее одной из ключевых проблем не только акушерства, но и здравоохранения в целом.</p></abstract><trans-abstract xml:lang="en"><p>Preeclampsia is not just an obstetric complication, but a systemic cardiometabolic stress test that reveals hidden risks to maternal and child health for decades to come. Recognized as one of the leading causes of maternal and perinatal mortality, preeclampsia goes far beyond the gestational period: it is a powerful predictor of future diseases in women, as well as a risk factor for developmental disorders, metabolic syndrome, and hypertension in offspring. This work presents a comprehensive analysis of risk factors and pathogenesis, clinical manifestations, modern approaches to prevention and treatment, as well as the socio-economic burden of preeclampsia on the healthcare system and society. Special attention is paid to the formation of an interdisciplinary management model for such patients, including the principles of lifelong follow-up. Preeclampsia requires rethinking: from episodic obstetric intervention to a strategy for long-term health care for two generations. This dictates the need for close cooperation between obstetricians and gynecologists, cardiologists, neurologists, endocrinologists and therapists to form a unified life strategy for protecting women’s health. Its consequences are systemic and prolonged, which makes it one of the key problems not only in obstetrics, but also in healthcare in general.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>преэклампсия</kwd><kwd>медико-социальные аспекты</kwd><kwd>эпидемиология</kwd><kwd>последствия</kwd><kwd>экономические затраты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>preeclampsia</kwd><kwd>medical and social aspects</kwd><kwd>epidemiology</kwd><kwd>consequences</kwd><kwd>economic costs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Martini C, Saeed Z, Simeone P, Palma S, Ricci M, Arata A, et al. Preeclampsia: Insights into pathophysiological mechanisms and preventive strategies. American Journal of Preventive Cardiology. 2025;23:101054. 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