urmjУральский медицинский журналUral Medical Journal2949-4389Ural State Medical University10.25694/URMJ.2018.09.16urmj-286Research ArticleМОЧЕКАМЕННАЯ БОЛЕЗНЬИспользование стромально-васкулярной фракции из аутологичной жировой ткани при стрессовом недержании мочи у мужчинUse of stromal-vascular fraction from autological fat tissue under stressed urinary disease in menПавловВалентин НиколаевичPavlovV. N.pavlov@bashgmu.ruИзмайловАдель АльбертовичIzmailovA. A.noemail@neicon.ruКурбангуловИльдар РаисовичKurbangulovI. R.noemail@neicon.ruДанилкоКсения ВладимировнаDanilkoK. V.noemail@neicon.ruСлесаренкоЯна СергеевнаSlesarenkoI. S.noemail@neicon.ruМаксимоваСерафима ЮрьевнаMaksimovaS. Y.noemail@neicon.ruФаргановАмир РафисовичFarganovA. R.noemail@neicon.ruВиландВольф ФердинандWielandW. F.noemail@neicon.ruПрантльЛукасPrantlL. .noemail@neicon.ruФельтхаусОливерFelthausO. .noemail@neicon.ruФГБОУ ВО Башкирский государственный медицинский университет Министерства здравоохранения Российской ФедерацииRussian FederationФГБОУ ВО Башкирский государственный медицинский университет МЗ РФRussian FederationУниверситетская клиника города РегенсбургRussian Federation201814042021093237Copyright © Павлов В.Н., Измайлов А.А., Курбангулов И.Р., Данилко К.В., Слесаренко Я.С., Максимова С.Ю., Фарганов А.Р., Виланд В.Ф., Прантль Л..., Фельтхаус О..., 20212021Павлов В.Н., Измайлов А.А., Курбангулов И.Р., Данилко К.В., Слесаренко Я.С., Максимова С.Ю., Фарганов А.Р., Виланд В.Ф., Прантль Л., Фельтхаус О.Pavlov V.N., Izmailov A.A., Kurbangulov I.R., Danilko K.V., Slesarenko I.S., Maksimova S.Y., Farganov A.R., Wieland W.F., Prantl L..., Felthaus O...Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.umjusmu.ru/jour/article/view/286

Цель работы - разработка малоинвазивного метода восстановления функции сфинктера мочевого пузыря с применением стромально-васкулярной фракции(СВФ) аутологичного жира. Материалы и методы. Пациентам с диагнозом стрессовое недержание мочи легкой и средней степеней тяжести выполнено трансуретральное введение аутологичной СВФ в зону наружного сфинктера мочевого пузыря. Выделение СВФ производилось неферментным методом при помощи тумесцентной липоаспирации. Полученный материал был направлен в лабораторию для исследования клеточного состава. результаты. На основании Pad test и опросников ICIQ-SF, QoL через 4 недели получены первые положительные клинические результаты и улучшение качества жизни. Выводы. В данной работе отмечено, что трансплантация СВФ из аутологичной жировой ткани представляется эффективным и безопасным методом лечения пациентов с недержанием мочи.

The aim of the work is to develop a minimally invasive method for restoring the function of the sphincter of the urinary bladder using autologous fat in the stromal-vascular fraction (SVF). Materials and methods. Patients with a diagnosis of stress urinary incontinence of moderate severity were given a transurethral injection of an autologous SVF into the zone of the external sphincter of the bladder. Isolation of SVF was performed by a nonenzymatic method using tumescent lipoaspiration. The resulting material was sent to the laboratory for the study of cellular composition. Results. Based on the Pad test and ICIQ-SF questionnaires, QoL received the first positive clinical results and improved quality of life after 4 weeks. Conclusions. In this work, it is noted that transplantation of SVF from autologous adipose tissue appears to be an effective and safe method of treatment of patients with incontinence.

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The authors declare that there are no conflicts of interest present.