urmjУральский медицинский журналUral Medical Journal2949-4389Ural State Medical University10.25694/URMJ.2018.09.36urmj-308Research ArticleАКТ МОЧЕИСПУСКАНИЯБотулотоксин типа А в лечении расстройств мочеиспускания у больных рассеянным склерозомBotulinum toxin type A for the treatment of low urinary tract dysfunction in patients with multiple sclerosisФилипповаЕкатерина СергеевнаPhilippovaE. S.filippova.cat@yandex.ruБаженовИгорь ВладимировичBazhenovI. V.noemail@neicon.ruФГБОУ ВО Уральский государственный медицинский университет Минздрава РоссииRussian Federation20181404202109142150Copyright © Филиппова Е.С., Баженов И.В., 20212021Филиппова Е.С., Баженов И.В.Philippova E.S., Bazhenov I.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.umjusmu.ru/jour/article/view/308

Наиболее распространенным методом лечения нейрогенной детрузорной гиперактивности у больных РС является назначение антихолинергических препаратов, однако действие м-холиноблокаторов часто оказывается недостаточным, либо они плохо переносятся в связи с большим количеством побочных явлений. В обзоре проанализированы данные литературы об эффективности и безопасности использования ботулинического токсина в лечении нейрогенной дисфункции нижних мочевыводящих путей у больных рассеянным склерозом.

Antiholinergic drugs remain the most popular treatment of the low urinary tract dysfunction in patients with multiple sclerosis, but often they are not effective or followed by marked side effects. Moreover, the evidence for their efficacy in multiple sclerosis is quite poor. In the review, the efficiency and safety of botulinumtoxin for neurogenic low urinary tract dysfunction in multiple sclerosis patients were analyzed according to the literature database.

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The authors declare that there are no conflicts of interest present.