urmjУральский медицинский журналUral Medical Journal2949-4389Ural State Medical University10.25694/URMJ.2018.11.17urmj-344Research ArticleНЕВРОЛОГИЯNEUROLOGYРоль нейропластичности в формировании психоэмоциональных нарушений при хронической головной боли напряженияThe role of neuroplasticity in the psychoemotional disorders formation in the chronic tension-type headacheКалинскийП. П.KalinskyP. P.noemail@neicon.ruТянК. В.TyanK. V.tyan_ksusha@mail.ruРакитоваА. В.RakitovaA. V.noemail@neicon.ruФГБОУ ВО «Тихоокеанский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииRussian Federation2018140420210113234Copyright © Калинский П.П., Тян К.В., Ракитова А.В., 20212021Калинский П.П., Тян К.В., Ракитова А.В.Kalinsky P.P., Tyan K.V., Rakitova A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.umjusmu.ru/jour/article/view/344

Исследование посвящено изучению взаимосвязи уровня нейротрофического фактора головного мозга (BDNF) в периферической крови с показателями болевого и психоэмоционального статуса у пациентов с хронической головной болью напряжения (ХГБН). В ходе проведенного исследования выявлено, что хроническая форма ГБН имеет в своей клинической картине отчетливую тревожно-депрессивную и астеническую симптоматику, при этом в сыворотке периферической крови выявляется выраженный дефицит BDNF.

The study was devoted to investigation of relationship between level of the brain-derived neurotrophic factor (BDNF) in the peripheral blood and pain, psychoemotioal state in patients with chronic tension-type headache (CTTH). The chronic form of TTH had a well-marked anxiety and depressive and asthenic symptoms, which leads to a significant deficiency of BDNF in the peripheral blood.

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The authors declare that there are no conflicts of interest present.