urmjУральский медицинский журналUral Medical Journal2949-4389Ural State Medical University10.25694/URMJ.2018.12.39urmj-392Research ArticleПСИХИАТРИЯИсследование эффективности применения воды, пересыщенной воздухом, для снижения тяжести последствий окислительного стресса у лабораторных животных. III. Сахароснижающее действие артезианской воды с нанопузырьковой газовой фазой: исследования на лабораторных крысах в условиях гиперкалорийной диеты и экспериментального сахарного диабетаEffect of use of water, supersaturated with air, to reduce the severity of the cvonsequence of laboratory animals oxidative stress. II. The hypoglycemic action of artesian water with gas nanobubble phase studied on lab rats in conditions of hypercaloric diet and experimental diabetБутолинЕ. Г.ButolinE. G.noemail@neicon.ruДаниловаО. В.DanilovaO. V.noemail@neicon.ruКанунниковаО. М.KanunnikovaO. M.noemail@neicon.ruЧучковаН. Н.ChuchkovaN. N.noemail@neicon.ruСметанинаМ. В.SmetaninaM. V.noemail@neicon.ruКожевниковВ. И.KozhevnikovV. I.noemail@neicon.ruТрубачевА. В.TrubachevA. V.noemail@neicon.ruФГБОУ ВО «Ижевская государственная медицинская академия» Минздрава РоссииRussian FederationФГБУН Удмуртский федеральный исследовательский центр Уральского отделения РАНRussian Federation201814042021012150154Copyright © Бутолин Е.Г., Данилова О.В., Канунникова О.М., Чучкова Н.Н., Сметанина М.В., Кожевников В.И., Трубачев А.В., 20212021Бутолин Е.Г., Данилова О.В., Канунникова О.М., Чучкова Н.Н., Сметанина М.В., Кожевников В.И., Трубачев А.В.Butolin E.G., Danilova O.V., Kanunnikova O.M., Chuchkova N.N., Smetanina M.V., Kozhevnikov V.I., Trubachev A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.umjusmu.ru/jour/article/view/392

Исследовано влияние воды с газовыми нанопузырьками на состояние и биохимические показатели крови крыс в условиях гиперкалорийной диеты и экспериментального диабета. Наблюдается благоприятное действие воды с нанопузырьками на крыс в условиях гиперкалорийной диеты и с экспериментальным аллоксановым и стрептозоциновым диабетом. У крыс, находящихся на несбалансированном рационе питания, включающем избыток жиров и углеводов, употребление воды с нанопузырьковой фазой сохраняет баланс в отношении показателей гликозилированного гемоглобина, способствует снижению веса и количества холестерина в сыворотке. У животных с экспериментальным диабетом прием обработанной воды в отсутствие сахароснижающей терапии приводит к понижению уровней глюкозы и гликозилированного гемоглобина. Эффект от приема воды в большей степени проявляется на крысах с аллоксановым диабетом. действие газовых нанопузырьков подобно действию препаратов-антиоксидантов.

The influence of water with gas nanobubbles on the condition and biochemical parameters of blood of rats in conditions of hypercaloric diet and experimental diabetes was studied. The beneficial effect of water with gas nanobubbles on rats in conditions of a reduced-calorie diet and streptozocin and experimental alloxan diabetes is observed. In rats, which were on an unbalanced diet, including excess fat and carbohydrates, the use of water with nanobubbles maintains a balance in terms of glycosylated hemoglobin, helps to reduce the weight and amount of cholesterol in the serum. In rats with experimental diabetes, the intake of treated water by rats, in the absence of hypoglycemic therapy, leads to a decrease in glucose levels and glycosylated hemoglobin. The effect of water intake is more pronounced in rats with alloxan diabetes. The action of the gas nanobubbles similarly the action of drugs-antioxidants.

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The authors declare that there are no conflicts of interest present.