Clinic-immunological aspects of chronic acquired toxoplasmosis in women of reproductive age

Abstract

Toxoplasmosis is a widespread opportunistic parasitosis. The frequency of Toxoplasma invasion in women with a history of complications is 54.8 ± 2.8%, and in women with normal pregnancies - 27.3 ± 3.6%. Clinically manifest form of chronic acquired toxoplasmosis was detected by immuno-statistical method in 24 women. The most frequent symptoms of intoxication in these women were weakness, fatigue, headaches, and pain in muscles and joints. In one third of women with chronic acquired toxoplasmosis, there was an increase in the lymph nodes, usually the occipital, cervical, submandibular. Of the gynecological pathology, the most frequently examined women had an inflammation of the uterus appendages (45.8%), and a spontaneous miscarriage was often noted in history. The immunogram of patients with chronic acquired toxoplasmosis was characterized by a decrease in absolute and relative number of T-lymphocytes - CD3 (541.3 ± 42.4 and 32.2 ± 9.9%), an increase in the number of NK-cells.