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Genital infection in women with spontaneous, timely and premature birth

https://doi.org/10.25694/URMJ.2018.13.51

Abstract

In recent years, the influence of genital infection on pregnancy and perinatal outcomes has been actively studied. The question arises-why genital infection during pregnancy in some cases can cause premature birth, and in others practically does not affect its course is not fully understood. Objective: to assess the features of history, pregnancy, structure of infectious pathology and its treatment in women with timely and premature birth. 112 women with infectious diseases of the vagina and cervix were retrospectively analyzed. It was found that the structure of infectious pathology of the lower reproductive tract in women with spontaneous preterm labor was represented by: cervicitis-29.4%, vaginitis-21.6%, their combination (cervicovaginitis) - 17.6%, bacterial vaginosis - 15.7%, vaginal dysbiocenosis - 15.7%. In very early and early preterm labor, the most common form of infectious pathology of the lower genitals was cervicovaginitis; in preterm labor - vaginitis. Structure of genital infections in patients with the timely childbirth: cervicitis is 27.9%, vaginitis - 26,2%, desbiens vagina - 16,4%, bacterial vaginosis -14.8%, cervicovaginitis is 14.8%. Conclusions: there were no differences in the structure of infectious pathology of the lower reproductive tract in women with spontaneous premature and timely delivery. In patients with genital infection, pregnancy in which ended spontaneous preterm birth significantly more often than in the comparison group there were: burdened obstetric and gynecological history, diseases of the urinary system, persistent threat of termination of pregnancy, placental insufficiency, iron deficiency anemia. In patients with spontaneous premature birth percentage of morphologically confirmed intrauterine infection was significantly higher than in women who gave birth at term and the set of morphological forms were distinguished by a higher degree of involvement of the tissues of the placenta in the inflammatory process (membranes, placenta).

About the Authors

V. F. Dolgushina
ГБОУ ВПО ЮУГМУ Минздрава России
Russian Federation


I. V. Kurnosenko
ГБОУ ВПО ЮУГМУ Минздрава России
Russian Federation


M. V. Astashkina
ГБОУ ВПО ЮУГМУ Минздрава России
Russian Federation


T. V. Nadvikova
ГБОУ ВПО ЮУГМУ Минздрава России
Russian Federation


L. A. Smolnikova
ГБОУ ВПО ЮУГМУ Минздрава России
Russian Federation


Yu. A. Fortygina
ГБОУ ВПО ЮУГМУ Минздрава России
Russian Federation


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Review

For citations:


Dolgushina VF, Kurnosenko IV, Astashkina MV, Nadvikova TV, Smolnikova LA, Fortygina YA. Genital infection in women with spontaneous, timely and premature birth. Ural Medical Journal. 2018;(13):78-82. (In Russ.) https://doi.org/10.25694/URMJ.2018.13.51

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ISSN 2071-5943 (Print)
ISSN 2949-4389 (Online)