Antioxidant therapy for brucellosis in women

Abstract

To study the antioxidant efficacy of aminodihydrophthalazinedione sodium (galavit), 180 patients with brucellosis were examined. The "before - after" study showed that complex therapy with the inclusion of galavit (intramuscularly at 100 mg twice a day for 2 days, then 100 mg every other day for 10-15 days) of patients with brucellosis of women is accompanied by a significant decrease in lipid peroxidation at all forms of brucellosis. Dynamic changes in the concentration of sulfhydryl groups in the blood tend to increase, while the concentration of disulfide groups increases with acute and subacute brucellosis, and in chronic brucellosis it decreases. Thioldisulfide coefficient in the treatment of galavit acute and chronic brucellosis is accompanied by an increase, with subacute - decrease. Complex treatment with galavit in acute and chronic brucellosis favorably affects the antioxidant system. The results of the study of the antioxidant activity of galavit allow us to recommend the drug as an additional means for increasing the effectiveness of treatment of all forms of brucellosis.