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Respiratory function after pulmonary tuberculosis treatment and causes of relapse

https://doi.org/10.52420/2071-5943-2022-21-4-85-92

Abstract

Introduction. Rehabilitation of patients after pulmonary tuberculosis treatment is a separate area of research in the field of phthisiology and pulmonology. The accumulation of data on the condition of patients after treatment in the near and distant period makes it possible to identify the factors of disease recurrence. Statistical estimation of pulmonary tuberculosis treatment outcomes provides the accumulation of parametric data on the results of therapeutic and rehabilitation measures. Purpose of the work was to analyze respiratory function of patients after treatment of pulmonary tuberculosis and possible causes of relapses of the disease by defining the dynamics of functional reserves depending on the form of the disease and methods of its treatment. Materials and methods. Scientific Russian and English literature was searched for the last five years. The literature search was performed in the PubMed, ResearchGate, Cyberlenica, and eLibrary databases. Results and discussion. It was established that respiratory function of patients after treatment of pulmonary tuberculosis depends on the form of the disease and methods of invasive intervention, as well as the algorithm of their choice in a particular case. Due to the variety of forms of pulmonary tuberculosis, the effects on respiratory function of such surgical methods of treatment as thoracoplasty, valve bronchoblocations, cavernotomy, resection continue to be studied. Studies of respiratory function have focused on patients with complicated, drug-resistant forms of tuberculosis. Causes and risk factors for tuberculosis recurrence have been found to include an increasing proportion of multidrug-resistant pathogens and comorbidities. The place of residence and social behavior of an individual are also singled out as risk factors. Conclusion. Current studies of respiratory function in patients after tuberculosis treatment have raised the question of the increase in the proportion of multidrug-resistant mycobacteria, and there are proposals for prevention of pulmonary tuberculosis recurrence by screening the treated patient and developing contra-cycling rehabilitation programs. Prognostic value of respiratory parameters after surgical treatment of pulmonary tuberculosis is insufficiently studied. At the same time the dynamics of functional reserves of the respiratory system allows to estimate the efficacy of surgical intervention.

About the Authors

Z. K. Dzhagaeva
North Ossetian State Medical Academy
Russian Federation

 Zarina K. Dzhagaeva  – MD 

 Vladikavkaz 



O. Z. Basieva
North Ossetian State Medical Academy
Russian Federation

Olga Z. Basieva  – MD 

 Vladikavkaz 



N. V. Kobesov
North Ossetian State Medical Academy
Russian Federation

 Nikolaj V. Kobesov  – MD 

 Vladikavkaz 



E. T. Tuallagova
Republican Clinical Center for Phthisiopulmonology
Russian Federation

 Evelina T. Tuallagova 

 Vladikavkaz 



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Review

For citations:


Dzhagaeva ZK, Basieva OZ, Kobesov NV, Tuallagova ET. Respiratory function after pulmonary tuberculosis treatment and causes of relapse. Ural Medical Journal. 2022;21(4):85-92. (In Russ.) https://doi.org/10.52420/2071-5943-2022-21-4-85-92

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ISSN 2071-5943 (Print)
ISSN 2949-4389 (Online)