Радиомика в лучевой диагностике биологических подтипов рака молочной железы (обзор литературы)
https://doi.org/10.52420/umj.23.4.41
EDN: DUJFIG
Аннотация
Введение. Рак молочной железы (РМЖ) занимает лидирующие позиции среди онкологических заболеваний, выявляемых у женщин. Ранняя диагностика и поиск предикторов злокачественных новообразований с использованием лучевых методов визуализации позволяет своевременно поставить диагноз и назначить лечение, что улучшает прогноз при РМЖ. Большая часть данных, полученных с помощью радиологического изображения, в значительной степени неспецифична на молекулярном уровне. Решением этих вопросов занимается радиомика, осуществляющая комплексную количественную оценку опухолевых фенотипов путем извлечения большого числа количественных признаков из медицинских изображений.
Цель — систематизация современных научных направлений радиомики в лучевой диагностике РМЖ.
Методы. Комплексный анализ электронных баз данных PubMed и eLibrary.ru за последние 5 лет.
Результаты. На основании изученных литературных данных определены основные перспективные научные направления развития радиомики в лучевой диагностике РМЖ: изучение распространенности заболевания, его факторов риска, новые скрининговые подходы в ранней диагностике; поиск специфических маркеров и доступных визуализации признаков определенного молекулярного потдтипа РМЖ; поиск прогностических предикторов и изучение точности прогноза на основании выявленных характеристик; определение возможностей персонализированной терапии, оценка наиболее эффективного лечения и современное ведение онкологических больных; расширение возможностей радиомики в сочетании с другими научными направлениями.
Ключевые слова
Об авторах
А. Ю. Попова
Свердловский областной онкологический диспансер
Россия
Россия
Алиса Юрьевна Попова✉ — заведующий отделением лучевой диагностики
Екатеринбург
В. Е. Гажонова
Центральная государственная медицинская академия
Россия
Россия
Вероника Евгеньевна Гажонова — доктор медицинских наук, профессор кафедры рентгенологии и ультразвуковой диагностики
Москва
М. В. Карташов
Свердловский областной онкологический диспансер
Россия
Россия
Максим Викторович Карташов — кандидат медицинских наук, руководитель диагностичского центра
Екатеринбург
С. А. Шевченко
Свердловский областной онкологический диспансер
Россия
Россия
Светлана Анатольевна Шевченко — кандидат медицинских наук, рентгенолог
Екатеринбург
О. С. Белова
Северный государственный медицинский университет
Россия
Россия
Ольга Сергеевна Белова — кандидат медицинских наук, доцент кафедры психиатрии и клинической психологии
Архангельск
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Рецензия
Для цитирования:
Попова АЮ, Гажонова ВЕ, Карташов МВ, Шевченко СА, Белова ОС. Радиомика в лучевой диагностике биологических подтипов рака молочной железы (обзор литературы). Уральский медицинский журнал. 2024;23(4):41–56. https://doi.org/10.52420/umj.23.4.41. EDN: DUJFIG
For citation:
Popova AY, Gazhonova VE, Kartashov MV, Shevchenko SA, Belova OS. Radiomics in the Radiation Diagnosis of Biological Subtypes of Breast Cancer (Literature Review). Ural Medical Journal. 2024;23(4):41–56. (In Russ.) https://doi.org/10.52420/umj.23.4.41. EDN: DUJFIG
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