Clinical, epidemiological and laboratory characteristics of HCV in women of fertile age

Abstract

Aim: to assess the effect of the natural course of chronic hepatitis C in young women, on fertile function. Material and methods. 71 patients with CHC were examined in a complex manner in comparison with the results of 32 healthy women of reproductive age, conducted on the basis of the infectious disease department of 5 VKG VNG RF (Ekaterinburg) in 2017-2018.Results: In interpreting the results it was found that in women with HCV infection, in comparison with healthy women, infertility is more often diagnosed, the frequency of infection with human papillomavirus is higher, the incidence of genital herpes, gastrointestinal tract diseases, ovarian cysts , uterine fibroids; with the progression of liver fibrosis, the levels of folicle-stimulating hormone (FSH) and testosterone decrease. Conclusion: The natural course of HCV-infection in fertile women is characterized by hormonal changes, mainly at the F3-F4 stage, moderate cytolytic syndrome, a decrease in vitamin D levels, and is accompanied by comorbidity from gynecological diseases and pathology of the gastrointestinal tract. Early diagnosis and timely treatment of HCV will prevent the development of violations of female reproductive function.