Dengue Fever in the Sverdlovsk Region: Clinical and Epidemiological Characteristics of Imported Cases
https://doi.org/10.52420/umj.24.6.7
EDN: AIJJJX
Abstract
Introduction. The spread of such a tropical infection as dengue fever (DF) is increasing in Russia. The increase in the number of imported cases is due to the general unfavorable situation of dengue in the world, the expansion of the range of the mosquito vector and the growing tourist flow to endemic regions. Repeated infection with different serotypes of the virus can lead to a severe course of the disease with manifestations of shock and hemorrhagic syndrome. Given this, the risk of developing severe dengue increases among tourists who repeatedly visit endemic countries.
Purpose of the study is to characterize the epidemiological and clinical features of imported cases of DF in the Sverdlovsk Region with a Sensor for increasing alertness regarding the current infection.
Materials and methods. A retrospective analysis of 13 cases of DF was performed on the basis of the City Clinical Hospital No. 40 in Ekaterinburg. Statistical data processing was carried out with the calculation of median, upper and lower quartiles, Mann-Whitney criterion, Spearman correlation coefficient.
Results. Cases of DF in the Sverdlovsk Region fit into the moderate form of the disease, however, a significant proportion of patients have warning signs: bleeding, hemorrhagic rash, moderate thrombocytopenia. Laboratory confirmation was obtained in 11/13 patients (84.62 %), four ELISA detected class G antibodies within 7 days of the onset of the disease, which may indicate reinfection.
About the Authors
S. A. Ustyugova
Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Sofya A. Ustyugova – Assistant of the Department of Infectious Diseases, Phthisiology and Pulmonology,
Institute of Preventive Medicine
Ekaterinburg
Competing Interests:
Alebay U. Sabitov is an editorial board member, Yulia B. Khamanova is an editorial council member of Ural Medical Journal, and they did not participate in reviewing the material or making a decision about its publication. The other authors declare the absence of obvious or potential conflict of interest.
A. U. Sabitov
Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Alеbay U. Sabitov – Doctor of Sciences (Medicine), Professor, Head of the Department of Infectious Diseases, Phthisiology and Pulmonology, Institute of Preventive Medicine
Ekaterinburg
Competing Interests:
Alebay U. Sabitov is an editorial board member, Yulia B. Khamanova is an editorial council member of Ural Medical Journal, and they did not participate in reviewing the material or making a decision about its publication. The other authors declare the absence of obvious or potential conflict of interest.
Yu. B. Khamanova
Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Yulia B. Khamanova – Doctor of Sciences (Medicine), Associate Professor of the Department of Infectious
Diseases, Phthisiology and Pulmonology, Institute of Preventive Medicine
Ekaterinburg
Competing Interests:
Alebay U. Sabitov is an editorial board member, Yulia B. Khamanova is an editorial council member of Ural Medical Journal, and they did not participate in reviewing the material or making a decision about its publication. The other authors declare the absence of obvious or potential conflict of interest.
N. A. Babintseva
City Clinical Hospital № 40
Russian Federation
Competing Interests:
Russian Federation
Nadezhda A. Babintseva – Infectiologist of the Infectious Diseases Department № 1
Ekaterinburg
Competing Interests:
Alebay U. Sabitov is an editorial board member, Yulia B. Khamanova is an editorial council member of Ural Medical Journal, and they did not participate in reviewing the material or making a decision about its publication. The other authors declare the absence of obvious or potential conflict of interest.
V. V. Belousov
Ural State Medical University; City Clinical Hospital № 40
Russian Federation
Competing Interests:
Russian Federation
Vitaly V. Belousov – Assistant of the Department of Infectious Diseases, Phthisiology and Pulmonology,
Institute of Preventive Medicine; Infectiologist, Head of the Infectious Diseases Department № 1
Ekaterinburg
Competing Interests:
Alebay U. Sabitov is an editorial board member, Yulia B. Khamanova is an editorial council member of Ural Medical Journal, and they did not participate in reviewing the material or making a decision about its publication. The other authors declare the absence of obvious or potential conflict of interest.
D. A. Soldatov
Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Dmitry A. Soldatov – Candidate of Sciences (Medicine), Associate Professor of the Department of Infectious
Diseases, Phthisiology and Pulmonology, Institute of Preventive Medicine
Ekaterinburg
Competing Interests:
Alebay U. Sabitov is an editorial board member, Yulia B. Khamanova is an editorial council member of Ural Medical Journal, and they did not participate in reviewing the material or making a decision about its publication. The other authors declare the absence of obvious or potential conflict of interest.
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Review
For citations:
Ustyugova SA, Sabitov AU, Khamanova YB, Babintseva NA, Belousov VV, Soldatov DA. Dengue Fever in the Sverdlovsk Region: Clinical and Epidemiological Characteristics of Imported Cases. Ural Medical Journal. 2025;24(6):7–18. (In Russ.) https://doi.org/10.52420/umj.24.6.7. EDN: AIJJJX
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