The role of inducing factors in the formation of Rendall plaques and the development of urolithiasis
https://doi.org/10.25694/URMJ.2018.09.12
Abstract
In this article, we present the main information about some promising markers of urolithiasis-substances formed on the surface of the transitional cell epithelium and involved in the inhibition or induction of crystal formation. The reason for their formation is still not fully understood. There is a hypothesis that they are inducers of calculus formation in the renal calyceal system and are directly related to Randall's plaques, whose role in the pathogenesis of ICDD remains a subject of discussion. In this regard, the study of the relationship of certain markers of urolithiasis with dysfunction of urothelium in the zone of formation of Randalla plaques is important for understanding the pathogenesis of this disease, for which an attempt has been made to thoroughly study Russian and English literature in databases (MEDLINE, PubMed, Medscape). A total of 126 sources were studied (all studies for the period 2000 - 2017), of which 15 publications of the most significant and relevant studies were selected for this review.
About the Authors
A. A. Kamalov
Медицинский научно-образовательный центр МГУ имени М.В. Ломоносов; МГУ имени М.В. Ломоносова
Russian Federation
Russian Federation
D. A. Okhobotov
Медицинский научно-образовательный центр МГУ имени М.В. Ломоносов; МГУ имени М.В. Ломоносова
Russian Federation
Russian Federation
A. N. Nizov
Медицинский научно-образовательный центр МГУ имени М.В. Ломоносов; МГУ имени М.В. Ломоносова
Russian Federation
Russian Federation
V. K. Dzitiyev
Медицинский научно-образовательный центр МГУ имени М.В. Ломоносов; МГУ имени М.В. Ломоносова
Russian Federation
Russian Federation
V. K. Karpov
Медицинский научно-образовательный центр МГУ имени М.В. Ломоносов; МГУ имени М.В. Ломоносова
Russian Federation
Russian Federation
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Review
For citations:
Kamalov AA, Okhobotov DA, Nizov AN, Dzitiyev VK, Karpov VK. The role of inducing factors in the formation of Rendall plaques and the development of urolithiasis. Ural Medical Journal. 2018;(9):10-13. (In Russ.) https://doi.org/10.25694/URMJ.2018.09.12
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