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Utility of 18F-FDG PET/CT in the diagnostics of Epilepsy

https://doi.org/10.25694/URMJ.2019.03.17

Abstract

Detecting the localization of epileptogenic focuses (seizure lateralization) in cases of epilepsy is an important diagnostic step aimed at choosing tactics and improving treatment outcomes. Currently, EEG (electroencephalography), magnetic resonance imaging (MRI) and, to a lesser extent, single photon emission computed tomography (SPECT) are most commonly used to diagnose epilepsy. The sensitivity of extracranial EEG does not exceed 56%, while at intracranial EEG the risk of complica-tions is high. Despite the fact that the diagnostic value of MRI is quite high, in a number of patients (especially with pharmacoresistant epilepsy), it is not possible to detect morphological changes. One of the most promising methods today is diagnostics using positron emission tomography, combined with computed tomography (PET/CT), using 18-fluorodeoxyglucose (18F-FDG) as a radiotracer. This article is a review of the literature on this issue in recent years. Data on informativity and diag-nostic value of PET / CT with 18F-FDG in patients with epilepsy are presented.

About the Authors

A. V. Aretinskiy
Центр ядерной медицины ООО «ПЭТ-Технолоджи»
Russian Federation


A. V. Zhilyakov
«Областной специализированный центр медицинской реабилитации “Озеро Чусовское”»
Russian Federation


V. B. Aretinskiy
«Областной специализированный центр медицинской реабилитации “Озеро Чусовское”»
Russian Federation


A. S. Shershever
ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России
Russian Federation


A. B. Isupov
«Областной специализированный центр медицинской реабилитации “Озеро Чусовское”»
Russian Federation


E. V. Shorikov
Центр ядерной медицины ООО «ПЭТ-Технолоджи»
Russian Federation


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Review

For citations:


Aretinskiy AV, Zhilyakov AV, Aretinskiy VB, Shershever AS, Isupov AB, Shorikov EV. Utility of 18F-FDG PET/CT in the diagnostics of Epilepsy. Ural Medical Journal. 2019;(3):25-29. (In Russ.) https://doi.org/10.25694/URMJ.2019.03.17

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ISSN 2071-5943 (Print)
ISSN 2949-4389 (Online)