Utility of 18F-FDG PET/CT in the diagnostics of Epilepsy

Detecting the localization of epileptogenic focuses (seizure lateralization) in cases of epilepsy is an important diagnostic step aimed at choosing tactics and improving treatment outcomes. Currently, EEG (electroencephalography), magnetic resonance imaging (MRI) and, to a lesser extent, single photon emission computed tomography (SPECT) are most commonly used to diagnose epilepsy. The sensitivity of extracranial EEG does not exceed 56%, while at intracranial EEG the risk of complica-tions is high. Despite the fact that the diagnostic value of MRI is quite high, in a number of patients (especially with pharmacoresistant epilepsy), it is not possible to detect morphological changes. One of the most promising methods today is diagnostics using positron emission tomography, combined with computed tomography (PET/CT), using 18-fluorodeoxyglucose (18F-FDG) as a radiotracer. This article is a review of the literature on this issue in recent years. Data on informativity and diag-nostic value of PET / CT with 18F-FDG in patients with epilepsy are presented.

эпилепсия, позитронно эмиссионная томография, совмещенная с компьютерной томографией, 18-фтордезоксиглюкоза, магнитно-резонансная томография (МРТ), электроэнцефалография (ЭЭГ), epilepsy, positron emission tomography/computed tomography, 18F-fluoro-2-deoxy-D-glucose, magnetic resonance imaging (MRI), electroencephalography (EEG)

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