Effectiveness of Anti-scar Therapy in the Rehabilitation of Children Following Surgical Treatment of Hand Fractures
https://doi.org/10.52420/umj.24.4.78
EDN: MLZQKJ
Abstract
Introduction. In certain cases, pediatric hand fractures may require surgical intervention, including open reduction, which is associated with an elevated risk of postoperative scar formation.
The aim of the study is to substantiate the feasibility of incorporating anti-scar therapy with а gel containing cepalin, heparin, and allantoin into the comprehensive rehabilitation of pediatric patients following surgical treatment of hand fractures.
Materials and methods. The prospective non-randomize study included 28 pediatric patients aged 5 to 17 years who underwent open reduction and fixation for hand fractures. The participants were divided into two groups: the main group (n = 15) received topical scar therapy with а gel containing cepalin, heparin, and allantoin for a period of 6 months, while the control group (n = 13) underwent standard rehabilitation without any targeted scar treatment. The condition of post-operative scars was assessed using the Manchester Scar Scale (MSS) at 6 weeks, 3 months, and 6 months postoperatively.
Results. In the main group, positive dynamics were observed across all scar characteristics, with statistically significant changes recorded for the “tissue tension” parameter — from (1.20±0.68) points at week 6 of follow-up to (0.53±0.52) points after 6 months (p = 0.009). Differences between the main and control groups reached statistical significance at the 6-month mark for the parameters “surface relief ” (0.60 vs. 1.00; p = 0.038) and “tissue tension” (0.53 vs. 1.31; p = 0.001). The difference in the total MSS score between the groups also reached statistical significance after 6 months (3.93 vs. 5.62; p = 0.007).
Conclusion. The application of а gel containing cepalin, heparin, and allantoin is associated with a reduction in scar-related changes across multiple parameters, thereby supporting its integration into comprehensive rehabilitation protocols for pediatric patients following surgical treatment of hand fractures.
Supporting agencies: The authors would like to thank the Departments of Traumatology and Orthopedics No. 1 and 2 at the Children’s City Clinical Hospital No. 9 (Ekaterinburg) for their assistance with conducting the study.
About the Authors
I. I. Gordienko
Ural State Medical University; Children’s City Clinical Hospital No. 9
Russian Federation
Competing Interests:
Russian Federation
Ivan I. Gordienko — Candidate of Sciences (Medicine), Associate Professor, Vice-Rector for Research and Innovations, Associate Professor of the Department of Pediatric Surgery, Institute of Surgery, Ural State Medical University; Orthopedic Traumatologist of the Traumatological and Orthopedic Department No. 1, Children’s City Clinical Hospital No. 9.
Ekaterinburg
Competing Interests:
None
A. E. Slukina
Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Anastasia E. Slukina — Specialist’s Degree Student of the Institute of Pediatrics and Reproductive Medicine, Ural State Medical University.
Ekaterinburg
Competing Interests:
None
D. L. Zornikov
Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Danila L. Zornikov — Candidate of Sciences (Medicine), Associate Professor, Associate Professor of the Department of Medical Microbiology and Clinical Laboratory Diagnostics, Institute of Preventive Medicine, Ural State Medical University.
Ekaterinburg
Competing Interests:
None
D. A. Pyatygina
Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Daria A. Pyatygina — Student of the Institute of Pediatrics and Reproductive Medicine, Ural State Medical University.
Ekaterinburg
Competing Interests:
None
N. A. Tsap
Ural State Medical University; Children’s City Clinical Hospital No. 9
Russian Federation
Competing Interests:
Russian Federation
Natalia A. Tsap — Doctor of Sciences (Medicine), Professor, Head of the Department of Pediatric Surgery, Institute of Surgery, Ural State Medical University; Pediatric Surgeon of the Department of Emergency Surgery, Children’s City Clinical Hospital No. 9.
Ekaterinburg
Competing Interests:
Natalia A. Tsap is an editorial board member of Ural Medical Journal, and she did not participate in reviewing the material or making a decision about its publication.
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Review
For citations:
Gordienko II, Slukina AE, Zornikov DL, Pyatygina DA, Tsap NA. Effectiveness of Anti-scar Therapy in the Rehabilitation of Children Following Surgical Treatment of Hand Fractures. Ural Medical Journal. 2025;24(4):78–89. (In Russ.) https://doi.org/10.52420/umj.24.4.78. EDN: MLZQKJ
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