Balloon Cell Nevus of the Skin in a Child: A Case Report
E. L. Kazachkov,
G. G. Popov,
M. K. Lebedeva,
T. E. Ilyina,
A. A. Dub,
Yu. A. Medvedeva,
E. A. Kazachkova,
A. I. Voropaeva https://doi.org/10.52420/umj.25.2.81
EDN: WTXXNP
Abstract
Introduction. A rare observation of balloon cell nevus (BN) in a 5-year-old child in the skin of the perianal region is given.
The purpose of this clinical case report is to present the morphological characteristics of an extremely rare skin pathology (BN) in a 5-year-old child in an unusual location (the perianal area) which determines the patient’s subsequent management.
Description of the clinical case. A rounded yellowish formation up to 0.8 cm was found in the perianal region. A formation with a smooth surface with a brownish tint of the periphery, elastic and displaceable together with the dermatoscope board. Under general anesthesia, a rounded formation of a symmetrical appearance, soft-elastic consistency was excised. Microscopically: nests of melanocytes at the border of the epidermis and dermis with transformation into large light balloon cells (up to 90 % of the tumor). Cell polymorphism, nuclear atypia, mitoses are absent. Immunohistochemically: positive expression of Melan-A, S100, HMB-45 by balloon cells, negative expression of panCK, CD68 and CD10.
Discussion of the clinical case. Morphological and immunohistochemical characteristics of the nevus with isolation of immunohistochemical markers of this tumor are discussed in detail. Literature data on the alleged genesis of BN are presented.
Conclusion. The morphological diagnosis in the above observation is extremely important, since it determines the vector of further studies and the tactics of patient management.
About the Authors
E. L. Kazachkov
South Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Evgeny L. Kazachkov — Doctor of Sciences (Medicine), Professor, Head of the Department of Pathological Anatomy and Forensic Medicine named after Professor V. L. Kovalenko
Chelyabinsk
Competing Interests:
Members of the editorial board of the Ural Medical Journal, did not participate in the review of the material or the decision to publish it
G. G. Popov
City Clinical Hospital No. 1
Russian Federation
Competing Interests:
Russian Federation
Georgy G. Popov — Head of the Pathological Department
Sterlitamak
Competing Interests:
The remaining authors declare no obvious or potential conflicts of interest
M. K. Lebedeva
South Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Marina K. Lebedeva — Postgraduate Student of the Department of Pathological Anatomy and Forensic Medicine named after Professor V. L. Kovalenko
Chelyabinsk
Competing Interests:
The remaining authors declare no obvious or potential conflicts of interest
T. E. Ilyina
South Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Tatyana E. Ilyina — Candidate of Sciences (Medicine), Assistant Professor of the Department of Pathological Anatomy and Forensic Medicine named after Professor V. L. Kovalenko
Chelyabinsk
Competing Interests:
The remaining authors declare no obvious or potential conflicts of interest
A. A. Dub
South Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Angela A. Dub — Doctor of Sciences (Medicine), Associate Professor, Professor of the Department of Patho‑ logical Anatomy and Forensic Medicine named after Professor V. L. Kovalenko
Chelyabinsk
Competing Interests:
The remaining authors declare no obvious or potential conflicts of interest
Yu. A. Medvedeva
South Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Yulia A. Medvedeva — Candidate of Sciences (Medicine), Associate Professor, Associate Professor of the Department of Pathological Anatomy and Forensic Medicine named after Professor V. L. Kovalenko
Chelyabinsk
Competing Interests:
The remaining authors declare no obvious or potential conflicts of interest
E. A. Kazachkova
South Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Ella A. Kazachkova — Doctor of Sciences (Medicine), Professor, Professor of the Department of Obstetrics and Gynecology
Chelyabinsk
Competing Interests:
Members of the editorial board of the Ural Medical Journal, did not participate in the review of the material or the decision to publish it
A. I. Voropaeva
South Ural State Medical University
Russian Federation
Competing Interests:
Russian Federation
Anna I. Voropaeva — Postgraduate Student of the Department of Microbiology, Virology, and Immunology, South Ural State Medical University
Chelyabinsk
Competing Interests:
The remaining authors declare no obvious or potential conflicts of interest
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Review
For citations:
Kazachkov EL, Popov GG, Lebedeva MK, Ilyina TE, Dub AA, Medvedeva YA, Kazachkova EA, Voropaeva AI. Balloon Cell Nevus of the Skin in a Child: A Case Report. Ural Medical Journal. 2026;25(2):81–91. (In Russ.) https://doi.org/10.52420/umj.25.2.81. EDN: WTXXNP
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