Cryoablation of prostate cancer in comparison with radical prostatectomy by extraperitoneoscopic access

Currently, prostate cancer is one of the most common oncological pathologies in Russia. We analysed the early results of surgical treatment of 259 patients with prostate cancer who were under our surveillance from 2016 to 2017. These patients were divided into two groups: first group underwent cryoablation of the prostate (31 patients), second group underwent radical prostatectomy without lymphadenectomy (39 patients). According to results of the preoperative examinations there was obtained no data on extracapsular tumour process, as well as on regional lymphadenopathy. All patients had no interest in sexual function. Prostate volume ranged from 12 to 65 cm3, PSA level ranged from 4.1 to 10 ng / ml, Gleason score ranged from 5 to 8 points. According to the first results we observed PSA level decrease in both groups of patients. Retention of urine, as well as the intensity of postoperative pain in patients undergoing cryoablation of the prostate is better in comparison with Laparoscopic radical prostatectomy, however, we continue evaluation of long-term oncological and functional results.

рак предстательной железы, криоабляция, лапароскопическая, экстраперитонеоскопическая радикальная простатэктомия, удержание мочи, Localized prostate cancer, Cryoablation, Laparoscopic radical prostatectomy, Urinary retention

1. Guidelines on Prostate Cancer. / N. Mottet, [et al.] // European Association of Urology - 2015.

2. Prostate cancer.Estimatedincidence, mortality&prevalence [Электронный ресурс] // World Health Organization. International Agency for Research on Cancer: [сайт], - 2012. URL: http://eco.iarc.fr/eucan/CancerOne.aspx?Cancer=29&Gender=1

3. Заболеваемость злокачественными новообразованиями в субъектах РФ ФГУ «ЦНИИОИЗ Минздравсоцразвития РФ». [Электронный ресурс] // ФГБУ «Центральный НИИ организации и информатизации здравоохранения» Министерства здравоохранения РФ: [сайт]. - 2007. URL: http://mednet.ru/images/stories/files/statistika/Zabolevaemost_ zlokachestvennymi_novoobrazovaniyami_v_subektah_RF.pdf

4. Социально значимые заболевания населения России в 2015 году ФГБУ «Центральный научно-исследовательский институт организации и информатизации здравоохранения» Министерства здравоохранения России. [Электронный ресурс]// ФГБУ «Центральный НИИ организации и информатизации здравоохранения» Министерства здравоохранения РФ: [сайт]. - 2016. URL: http://nednet.ru/images/storiesfles/ statistika/socialno-znachimie_zabolevaniya/ssz2015.pdf

5. Mortality indicator database. Standardized death rates per 100000, malignant neoplasm of prostate [Электронный ресурс] // World Health Organization, regional office for Europe. European mortality database: [сайт]. - 2016. URL: http://data.euro.who.int/hfamdb/

6. Говоров, В.А. Криоабляция в лечении рака предстательной железы: диссертация доктора Медицинских наук: 14.01.23/А.В.Говоров - Москва, 2016.

7. Irreversible electroporation : Current value for focal treatment of prostate cancer / Wendler JJ, [et al.] // Urologe. A. - 2015 Vol. 54 №6 - P. e854-862.

8. The safety and efficacy of irreversible electroporation for the ablation of prostate cancer: a multicentre prospective human in vivo pilot study protocol / Bos W., [et al.] //BMJ Open. - 2014. - Vol. 4, №10 e006382.