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Effect of use of water, supersaturated with air, to reduce the severity of the cvonsequence of laboratory animals oxidative stress. I. The influence of water, supersaturated with air, on the bioelectrical mobility of the isolated cells

https://doi.org/10.25694/URMJ.2018.10.37

Abstract

The objects of the study were erythrocytes and buccal epithelium cells. Hemolysis of erythrocytes and microelectrophoretic mobility of cells in artesian water supersaturated with nitrogen, oxygen, argon, carbon dioxide and oxygen were investigated. It was experimentally established that water with gas nanobubbles has a cytoprotective and membrane-resistant effect in the conditions of osmotic and toxic effects on both red blood cells and epithelial cells of the buccal epithelium, while having an activating effect on the cell, its compartments (core) and plasma membrane. The intensity of cell response depends on the nature of the gas phase nanomaterialy: nanomaterialy phase Ar activates cells to a lesser extent than the phase of air and O2. This dependence correlates with the solubility of gases. The activity is also due to the duration of water treatment.

About the Authors

N. N. Chuchkova
ФГБОУ ВО «Ижевская государственная медицинская академия» Минздрава России
Russian Federation


A. A. Solovyev
ФГБОУ ВО «Ижевская государственная медицинская академия» Минздрава России
Russian Federation


O. M. Kanunnikova
ФГБУН Удмуртский федеральный исследовательский центр Уральского отделения РАН
Russian Federation


V. V. Aksenova
ФГБУН Удмуртский федеральный исследовательский центр Уральского отделения РАН
Russian Federation


V. I. Kozhevnikov
ФГБУН Удмуртский федеральный исследовательский центр Уральского отделения РАН
Russian Federation


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Review

For citations:


Chuchkova NN, Solovyev AA, Kanunnikova OM, Aksenova VV, Kozhevnikov VI. Effect of use of water, supersaturated with air, to reduce the severity of the cvonsequence of laboratory animals oxidative stress. I. The influence of water, supersaturated with air, on the bioelectrical mobility of the isolated cells. Ural Medical Journal. 2018;(10):155-161. (In Russ.) https://doi.org/10.25694/URMJ.2018.10.37

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