The aim of this study was to study the bioelectrical activity of the masticatory muscles in 50 patients with primary traumatic occlusion in the stage of decompensation (26 women and 24 men) and in 50 patients with combined traumatic occlusion (27 women and 23 men) in central occlusion. Registration of bioelectric potentials was carried out by interference electromyography using the Neuroromyograph Synapsis (STATOKIN) electroneuromyography complex with compression of the jaws in the usual occlusion before and after 3 and 6 months after prosthetic treatment. After prosthetics in patients with primary traumatic occlusion in the stage of decompensation and in patients with combined traumatic occlusion, there was a normalization of the distribution of the masticatory pressure by carrying out rational prosthetics in both groups, which facilitated the gradual normalization of the function of the masticatory muscles with the approach of their activity to the controls obtained in the group.

The study of the periodontal condition in patients with primary traumatic occlusion in the stage of decompensation was performed in 50 patients (26 women and 24 men) before the beginning of prosthetic treatment, and 3 and 6 months after prosthetics using the index OHI-S, the index of hemorrhagic gums Muhlemann-Cowell and Russel periodontal index according to the generally accepted method. The statistical analysis showed that the differences between all time intervals can be considered statistically significant at the level of p <0.01. Dynamic observation showed a persistent progressive improvement in the hygienic state of the oral cavity. The indicators of hemorrhage and periodontal index significantly decreased after 3 months after prosthetics, but after 6 months there was a slight tendency to increase, which allows talking about the relative stabilization of periodontal conditions and the effectiveness of orthopedic treatment.

The results of the experimental study are presented, in which cavities under the all-ceramic inserts of the in-ley type were prepared on 20 premolars and molars of both jaws removed medically. Optical impressions were obtained with the help of a domestic VT Dental scanner. The tabs were made using the CAD \ CAM method. After fixing the inserts, longitudinal teeth sections were made to study the accuracy of the attachment of the inserts by scanning electron microscopy. Conclusions: The tightness of the all-ceramic inlays in the cavities, which are made using the VT Dental scanner (Russia), has the same results as the best world analogues of the scanning device.

To determine the dependence of the blood perfusion volume in the periodontal tissues on the degree of stress resistance and anxiety level in patients, we performed an examination, a survey and an index evaluation of periodontal disease. We also found out the level of emotional and psychological stress, the degree of anxiety and neurotic state in the subjects. Using laser Doppler flowmetry with a spectral analysis of blood flow oscillations, using the customary method on the LAKCOP apparatus, using a personalized kappa with a detachable fixative, the data on the parodontal blood supply parameters were determined. Patients with low stress tolerance and a high level of anxiety have significant differences from other study groups in virtually all parameters of dental status, in particular, with an increase in the level of psychoemotional tension, the intensity of carious diseases and inflammatory diseases of periodontal tissues increases. We got a significant decrease in the blood flow velocity in patients with psychoemotional stress .The rate of hemodynamics in the microcirculatory bed of periodontal tissues in patients of the control group is 1.5 times lower than in the patients of the third group and in 1.8 times in the patients of the fourth group.

For the purpose of assessing the prevalence of periodontal tissue diseases among sportsmen of the Urals region, 52 sportsmen aged from 18 to 30 years were subjected to preventive examinations. The control group consisted of 50 students of UGMU, who are engaged in amateur sports. All patients underwent dental examination, which included basic and additional methods (definition of indices of oral hygiene: OHI-S; assessment of the condition of periodontal tissues (PMA), determination of the index of bleeding gums in inflammatory periodontal diseases (IR) M llmann), sialometry, oral fluid analysis and micronucleus test of buccal epithelium. The index evaluation of the condition of periodontal tissues and oral hygiene showed an unsatisfactory level of hygiene and a high prevalence of inflammatory diseases of periodontal tissues among athletes. Nonspecific parameters of inflammation in the oral fluid were revealed, as well as pronounced changes in cytogenetic parameters in the buccal epithelium in the main study group.

Goal. Evaluation of the effectiveness of the use of collagen membrane COLLOST® when closing the wound surface during surgical correction of the mouth of the mouth in patients with complete absence of teeth in the region of the lateral sections of the lower jaw. Methods. 18 patients were operated on by methods of deepening the vestibule of the oral cavity by Clark. Patients of the main group (10 people) wound surface during the operation was closed with collagen membrane COLLOST®, and the wound surface to patients of the comparison group (8 people) was left open and the wound was healed by secondary tension.Results. Based on the results of surgical correction of the oral cavity in the lateral parts of the lower jaw, it was revealed that when the collagen membrane of COLLOST® is used, the patients do not have a wound surface in the region of the newly formed vestibule of the oral cavity, there is no pain effect and the depth of the vestibule is formed 3-5 mm more from initial values.Conclusions. The use of collagen membrane COLLOST® should be recommended in the conduct of vestibuloplastic operations in order to close the wound surface of the newly formed vestibule of the oral cavity.

One of the reasons for the increase in the incidence of caries is the deficit of chewing load. The dental training developed by us allows to fill it. The conducted research allows to speak about the positive impact of dental training on the blood supply to the jaws, salivation and resistance of enamel as a preventive direction to improve dental status.

The aim of our study was to identify possible acute and subchronic toxicity, to establish the safety of the use of a composition based on cell products under experimental conditions in three types of laboratory animals, with different routes of administration. The studies were carried out on white mongrel mice weighing 19-21 g, white rats of the Wistar lineage weighing 190-240, rabbits of the Chinchilla breed with a mass of 2.8-3.6 kg of both sexes. The results of the conducted studies showed that the composition based on cell products in native form and as a 10% suspension does not cause acute and subchronic toxicity. The different degree of expression of motor activity and behavior, before and after administration of 0.4 ml of a 10% suspension of the test composition, became the main criterion for the separation of this population of females and males into subpopulations by the level of anxiety. The composition based on cell products does not cause a local irritant effect on mucous membranes and skin of rabbits. The test composition with subchronic application does not show sensitizing properties.

In this article the ecological characteristic of microbiocenosis of the oral cavity is given, which allowed to estimate not only the composition of biocenosis but also its ecological significance in the development of major dental diseases in young people living in a large industrial region on the example of Ufa. The study of microbiocenosis of the oral cavity showed that in this category of persons there are changes in the structure of microorganisms with the domination of opportunistic microorganisms, due to the decrease in the incidence of resident representatives. To

The application of the "Gluma Desensitizer" and the «step-by-step» method Jacobsen P.L. (USA) for the treatment of dentine sensitivity in patients with atherosclerotic hemodynamically significant stenosis of common carotid or external carotids. Objectives. Treatment of the sensitivity of dentin, associated with exposure of the necks and roots of teeth as a result of periodontitis, in patients with carotid pathology. Methods. Examination of patients, professional oral hygiene, treatment of hyperesthesia of teeth with the application of the "Gluma-desensetizer" (two sessions of applying the desensetizer to the exposed areas of the teeth). Repeated examination of the patient after 3 weeks. If conservative dysfunction did not help, we applied endodontic treatment. Results. After 3 weeks, 97% of patients did not complain of hyperesthesia. Endodontic treatment was performed in 3% of patients. Conclusions. The use of the "Gluma-desensetizer" and the «step-by-step» treatment of Jacobsen P.L. n is highly effective.

Disturbance of nasal breathing is one of the factors which is leads to narrow maxilla. To select optimal treatment we need to study the width of upper incisors, base of the nose with a narrow maxilla and the convergence of the incisors’ roots. The dynamics of the development of upper jaw in 50 children aged between 9 to 11 years old, who have different degrees of narrow maxilla during orthodontic treatment has been studied. It was established that correction the position of upper incisor is a key component in the correction of the maxillofacial region with narrow maxilla, ensures the correct development of the nasomaxillary area in accordance with anatomical standard for children 9-11 years old.

The article presents a review of the scientific literature containing data on the possibilities of modern preventive measures of caries of hard tissues of teeth in children of primary school age. Statistical reviews indicate a high prevalence of this pathology before the present time and the most significant one in the structure of STO-matological diseases. The analysis shows the necessity of studying the existing research and knowledge in the field of preventive dentistry, contributing to the development and implementation of the most effective preventive measures.

Authors, based on the analysis of scientific literature, analyzed the possible use of an innovative product - the dentofacial simulator "Dentafit", which replenishes the deficit of the masticatory load.. The Company now its industrial production. Conduct research the necessity of using dentoalveolar training to improve the dental status, as well as the prevention and treatment of dentofacial anomalies.

To assess the level of dental health of key WHO groups, as well as the intensity and prevalence of caries and non-carious lesions, 660 young people were examined according to the procedure recommended by WHO in the Russian Federation. Epidemiology of the main dental diseases in Ufa is characterized by a significant spread of caries to 98 ± 0,001%, while the intensity of the carious process averaged 12.29 ± 0.97, the prevalence of non-carious lesions was 60%.

The aim of the study was to study the safety and efficacy of endovascular radiofrequency denervation of the renal arteries in the combined therapy of patients with resistant arterial hypertension. Endovascular radiofrequency denervation of renal arteries was performed in 27 patients. The observation period was 1,3,6,12 months after the procedure, with the assessment of adverse events and daily measurement of blood pressure. As a result, the clinical significance of the method to reduce systolic and diastolic blood pressure was determined according to the results of a year's observation, which in turn reduces the risk of cardiovascular complications, as well as the risk of death.

An increase in the volume of cardiosurgical interventions is accompanied by an increase in their effectiveness and quality. Currently, the main methods of surgical treatment of coronary artery disease are coronary stenting and coronary artery bypass grafting (CABG). The number of CAB operations performed in our country over the past 5 years has increased more than 5 times [1]. Rehabilitation assistance to patients who underwent reconstructive surgery at heart continues to develop actively, but many aspects of this complex process have not been sufficiently studied. The prognosis of the patient who underwent CABG depends on the effectiveness of rehabilitation and secondary prevention of IHD, which consists in the drug correction of dyslipidemic, hemorheological, hyperoxidative syndromes that accelerate the atherosclerotic process.

The results of the examination of the cortisol content in the blood during general anesthesia in 60 patients operated on for thyroid nodular formations are analyzed. The first group (main group) -40 patients in whom ALV was carried out using the laryngial mask (LM); The 2nd (control) group - Ventilation was performed with intubation of the trachea (IT). The level of cortisol in the blood in both groups was determined in 4 stages: 1- the day before the operation; 2- when applying LM and IT; 3- with stromectomy and 4 th stage - with the application of the last sutures to the wound of the neck. The results of the studies showed that in both methods of ventilation the sympathetic-adrenal system is adequately protected, however, anesthesia with LM causes less stress response; so if during the imposition of LM the level of cortisol increased by 33% from the initial index, then in the second group (intubation of the trachea) this reached up to 35.7% (P <0.05). Similar proportions were more or less characteristic in the 4th stage. However, during the peak of the operation (stage 3 of the examination) in both groups, the level of cortisol in the blood was approaching the baseline, which proved the adequacy of anesthesia in both groups. In addition, the use of LM in the replacement of tracheal intubation, along with the least response of the stressful response of the body, can reduce the occurrence of unwanted symptoms in the postoperative period in the upper respiratory tract.

The material was collected in the course of a retrospective study of the medical documentation of the Department of thoracic surgery of the SBU NSO state Novosibirsk regional clinical hospital. During the period from 2009 to 2017, 140 patients with bullous lung emphysema were included in the study, who underwent bull excision or apparatus resection of the lung area and Subtotal parietal pleurectomy. The patients ' age ranged from 15 to 60 years and averaged 29.46 years(Me 27 (23.0;34.0)). At the same time, 108 patients, which accounted for more than 70% were patients aged 21 to 40 years, i.e. the most able-bodied age. One of the serious complications in the postoperative period was air leakage through pleural drains. Proposed and implemented in the practice of the surgical thoracic Department method of early (2-3 days postoperative) drug resistant patients with discharge air and the analysis of the results of this method in comparison with late (more than 3 days since the operation) bronchomalacia. To do this, patients were divided into 2 groups. The first group included 11 patients to whom the bronchoblocker was installed later than 3 days after the intervention. The second group included 21 patients who had the blocker installed on 2-3 days of the postoperative period. There were no statistically significant differences between the groups by age, sex, method of influence on the bullous-altered fragment of pulmonary tissue (p>0.05).

Diseases of the temporomandibular joint (TMJ) are one of the most common pathologies of the maxillofacial region both in Russia: up to 87%, and abroad up to 75%. We set a goal: to study the bioelectric potential of the actual chewing and temporal muscles with each chewing motion in patients with bilateral osteoarthritis of the temporomandibular joint with various functional tests. To assess the symmetry of the masticatory muscles, to analyze the ratio of the chewing time to the resting time (coefficient K), to compare the results with the norms of the norm.

The aim of the research is to study the clinical and biochemical, immunological indicators in dynamics of treatment of complicated chronic pyelonephritis during intercurrent diseases. The conducted researches showed that metabolic changes in this patients are characterized by structural and functional instability of cytomembranes and reduction of immunological resistance of organism. The additional insertion of antioxidant therapy in standard scheme of treatment is substantiated by the results of clinical and biochemical, immunological research

Before the clinical researches, the experimental researches to study the influence of enterosgel, polisorb MP and activated carbon on absorbation of microogranisms from test-culture were conducted. The observations invitro showed that sorbent enerosgel and activated carbon in relation to the absorption of E. Coli revealed that this sorbents adsorb E.Coli actively and polisorb MP adsorbs even faster. Study of the absorption of sugar by enerosgel, polisorb MP and activated carbon from 5% sugar solution showed that enterosgel took more than a half of glucose from the original solution during 3 hours, activated carbon and polisorb MP don’t have this level of absorption. The comparative analysis of general and biochemical blood analysis and urine of patients, who have puru-lent pyelonephritis in combination with diabetes mellitus, was conducted. The main group of 26 people, who received enterosgel in the amount of 22 grams for half an hour before meals, to relieve endotoxemia and reduction of glucose in blood, and 26 people from control group, who received traditional treatment. After all experimental researches we decided that enterosgel can be prescribed in complex treatment of se-vere forms of purulent pyelonephritis in combination with diabetes mellitus. The analysis of conducted treatment testifies that complex treatment of purulent pyelonephritis in combina-tion with diabetes mellitus by injection of enterosgel leads to the reduction of direct toxic influence on tub-ular on glomerular apparatus of kidneys with improvement of renal blood circulation due to normalization of rheological parameter of blood. The evidence is the improvement of endotoxemia and homeostasis. In this regard, it is necessary to emphasize that enterosgel normalizes glucose in blood, directly participate in regulation of sugar in blood that stimulate the reduction of diabetes complications. The data of sugar dy-namics, the improvement of glomerular function and the normalization of immunity indicators testifies this.

The stricture of the urethra remains a complex issue of operative urology at the present stage of development of this specialty. Our work is devoted to one of the methods of anti-relapse therapy - the use of cytotoxic drugs. The experiment shows the effect of the drug "Mitomycin" on the scar process in the mucous urethra of rabbits. It was proved that the cicatricial process in the urethra is less pronounced in the submucosal administration of the drug "Mitomycin".

The aim is to study the review of domestic and foreign literature on the prevention and treatment of pelvic floor dysfunction. Material and methods. The data of 87 foreign and domestic sources found in international free access databases were analyzed. Results. The detection of pelvic floor dysfunction in the female population ranges from 32-72% in the late stages of development. According to the literature, at 6 weeks after birth, 32% of women who had labor through natural birthmarks and 35% had a prolapse after caesarean section (p = 0.805). In comparison with nulliparous women, the odds ratio (OR) of the presence of grade II prolapse in POPQ and grade III or IV prolapse associated with repeated births is 2.95 (95% CI: 2.06-4.24) and 1.01 ( 95% CI: 0.40-2.79), respectively. The main cause of DTD is pregnancy and childbirth, which can lead to injuries m. levator ani and f. pubocervicalis. In addition, mechanical stretching, ischemia, denervation of the muscular-fascial complex, and the inadequacy of the repair processes of the elastic fibers of the vaginal and pelvic floor tissues are important. Conclusion: Obtained data on DTD may indicate the prevalence of young women, testify to the need to develop an algorithm for early detection of the disease.

The goal is to analyze the health indicators of the children's population and assess the quality of preventive examinations of minors in the Sverdlovsk region. Materials of the research. Data on the health status of the children of the Sverdlovsk region on the results of preventive medical examinations (PE) for the period 2013-2017 are presented. for different age groups. A sample analysis of the primary medical records of children's polyclinics is performed. Results of the study. The analysis of the structure of pathological affection, depending on the age of the newly diagnosed diseases, the definition of the needs for additional consultations, studies, treatment, as well as the coverage of the data after the completion of the preventive examination. Deficiency of doctors of the experts participating in carrying out of preventive medical examinations of children is established. Identified defects in making conclusions on the results of medical examination by specialists, referral to additional consultations, treatment and treatment. Conclusions. A high level of coverage of the child population of the software was registered. Tendencies in changes in morbidity rates were typified by a decrease in pathological affection in most classes of diseases. The leading causes of morbidity in children 0-14 years old are as follows: diseases of the nervous system, digestive organs, musculoskeletal system, in adolescents - eye diseases, musculoskeletal system and digestive organs. In order to improve the quality of preventive examinations in the region, it is necessary to strengthen internal control over the completeness of the software, the correctness of recording the results, and the direction of the needy for the second stage of medical examination.

In order to develop a system of measures to improve the quality of preventive medical examinations (PMO) of working urban population in 2017 on the basis of 3 polyclinics of Makhachkala, a study was conducted to study the opinion about the quality of preventive examinations among the working population. A survey was conducted and 675 questionnaires were statistically processed to study the opinion of the working population to preventive medical examinations. As a result of the analysis of the sociological survey data, the main reasons for the dissatisfaction of the population with outpatient care were identified: low equipment of medical and diagnostic equipment, the lack of doctors of narrow specialties, insufficient qualification of doctors, irrational schedule and mode of operation, queues to doctors and auxiliary rooms, inattention, non-tactful attitude of medical staff to patients, etc.

We presented the results of health-saving technologies in shaping the processes of biological and socio-psychological adaptation of six-year-old children with delay of mental development in the conditions of pre-school compensatory educational organization. It was established that the multifaceted system of medical care of these children, taking into account the integration of the activities of hygienists, teachers, psychologists, special education teachers, speech therapists, provides positive dynamics of biological and socio-psychological adaptation indices. It is shown that the proposed recommendations on the organization of health-saving technologies can be used to substantiate the priority areas of correcting and promoting the health of children with a delay in mental development in the conditions of a pre-school compensatory educational organization.

A decrease in interleukin-2 (丨L-2) in the serum of patients with a recurrent form of genital herpes was registered. To correct the revealed disorders, recombinant IL-2 was used. A comparative analysis of the efficacy of recombinant IL-2 in the complex therapy of recurrent genital herpes in 45 women aged 20 to 35 years, diagnosed on the basis of a set of clinical and laboratory indicators and the collection of anamnestic data. It was shown that the use of a complex therapy regimen including Valaciclovir 500 mg twice a day for 5 days Roncoleukin subcutaneously once a day for 3 days for 0.5 mg with an interval of 3 days resulted in the restoration of 丨L-2 content and contributed to a decrease in relapses of herpetic infection.

The technology of control of laser action on the retina, based on the use of optoacoustic sounding, is discussed. A 丨ow-power probing laser with pulses of 7-10 ns generates acoustic waves in the retinal pigment epithelium, which are detected by an acoustic receiver located on a three-mirror lens placed on the cornea of the eye. The amplitude of the acoustic wave makes it possible to judge the value of the optical absorption coefficient at this point, a value determining the heating temperature of the region after the action of the therapeutic laser. To calculate the temperature field, a three-dimensional model of thermal conductivity is used, which allows determining the temperature distribution at any point during heating by the coagulator, and also after it is turned off. The experiment was carried out on 2 eyes of 1 rabbit of the chinchilla gray breed in vivo, it was planned to obtain 2 degrees of L 'Esperance coagulation according to the temperature distribution. In total, 17 out of 20 delivered at different points of coagulation were recognized as coagulants of the 2nd degree according to the classification of L 'Esperance.

The study examined the developmental status of children with dysplasia of the urinary system aged 6 to 10 years with a duration of the disease from 1 month to 5 years. Based on the data obtained from anthropometric and functional studies, physical development evaluation, age determination, assessment of biological age, assessment of physical preparedness, conclusions were drawn that the physical state is characterized by a reliable decrease in indicators and the disharmonization of physical development, the development of the phenomenon of deceleration, systems and overall physical performance in comparison with peers who do not have this pathology ogii. Lower values of the signs had children with impaired renal hemodynamics.